Alpha-Hemolysin is an extracellular protein toxin (107 kDa) produced by some pathogenic strains of Escherichia coli. Although stable in aqueous medium, it can bind to lipid bilayers and produce membrane disruption in model and cell membranes. Previous studies had shown that toxin binding to the bilayer did not always lead to membrane lysis. In this paper, we find that alpha-hemolysin may bind the membranes in at least two ways, a reversible adsorption and an irreversible insertion. Reversibility is detected by the ability of liposome-bound toxin to induce hemolysis of added horse erythrocytes; insertion is accompanied by an increase in the protein intrinsic fluorescence. Toxin insertion does not necessarily lead to membrane lysis. Studies o...
Uropathogenic strains of E. coli deliver the toxin alpha-hemolysin (HlyA) to optimize the host envir...
α-Hemolysin (HlyA) is an exotoxin secreted by some pathogenic strains of Escherichia coli that cause...
α-Hemolysin (HlyA) is an extracellular protein toxin secreted by Escherichia coli that acts at the l...
alpha-Hemolysin is an extracellular protein toxin (107 kDa) produced by some pathogenic strains of E...
Alpha-Hemolysin is an extracellular protein toxin (107 kDa) produced by some pathogenic strains of E...
Abstractα-Hemolysin (HlyA) is a protein toxin, a member of the pore-forming Repeat in Toxin (RTX) fa...
alpha-Haemolysin is an extracellular protein toxin (approximately 107 kDa) secreted by Escher...
Abstractα-Hemolysin (HlyA) is an extracellular protein toxin secreted by Escherichia coli that acts ...
α-Hemolysin (HlyA) is an extracellular protein toxin (117 kDa) secreted by Escherichia coli that tar...
Abstractα-Haemolysin interaction with model membranes has been investigated by a 2-fold procedure. F...
α-Hemolysin (HlyA) is a protein toxin, a member of the pore-forming Repeat in Toxin (RTX) family, se...
Abstractα-Hemolysin (HlyA) is an extracellular protein toxin (117 kDa) secreted by Escherichia coli ...
Alpha-Hemolysin is synthesized as a 1024-amino acid polypeptide, then intracellularly activated by s...
Alpha-Hemolysin is synthesized as a 1024-amino acid polypeptide, then intracellularly activated by s...
Several toxins that interact with animal cells present some kind of interaction with cholesterol (Ch...
Uropathogenic strains of E. coli deliver the toxin alpha-hemolysin (HlyA) to optimize the host envir...
α-Hemolysin (HlyA) is an exotoxin secreted by some pathogenic strains of Escherichia coli that cause...
α-Hemolysin (HlyA) is an extracellular protein toxin secreted by Escherichia coli that acts at the l...
alpha-Hemolysin is an extracellular protein toxin (107 kDa) produced by some pathogenic strains of E...
Alpha-Hemolysin is an extracellular protein toxin (107 kDa) produced by some pathogenic strains of E...
Abstractα-Hemolysin (HlyA) is a protein toxin, a member of the pore-forming Repeat in Toxin (RTX) fa...
alpha-Haemolysin is an extracellular protein toxin (approximately 107 kDa) secreted by Escher...
Abstractα-Hemolysin (HlyA) is an extracellular protein toxin secreted by Escherichia coli that acts ...
α-Hemolysin (HlyA) is an extracellular protein toxin (117 kDa) secreted by Escherichia coli that tar...
Abstractα-Haemolysin interaction with model membranes has been investigated by a 2-fold procedure. F...
α-Hemolysin (HlyA) is a protein toxin, a member of the pore-forming Repeat in Toxin (RTX) family, se...
Abstractα-Hemolysin (HlyA) is an extracellular protein toxin (117 kDa) secreted by Escherichia coli ...
Alpha-Hemolysin is synthesized as a 1024-amino acid polypeptide, then intracellularly activated by s...
Alpha-Hemolysin is synthesized as a 1024-amino acid polypeptide, then intracellularly activated by s...
Several toxins that interact with animal cells present some kind of interaction with cholesterol (Ch...
Uropathogenic strains of E. coli deliver the toxin alpha-hemolysin (HlyA) to optimize the host envir...
α-Hemolysin (HlyA) is an exotoxin secreted by some pathogenic strains of Escherichia coli that cause...
α-Hemolysin (HlyA) is an extracellular protein toxin secreted by Escherichia coli that acts at the l...