Memory T cells are heterogeneous in phenotype and function. In this issue of Immunity, Newell et al. (2012) use a new flow cytometry platform to show that the functional heterogeneity of the human T cell compartment is even greater than previously thought
Phenotypic and functional heterogeneity are the hallmarks of effector and memory T cells. Upon antig...
The probabilistic expression of cytokine genes in differentiated T helper (Th) cell populations rema...
An important aspect of immune monitoring for vaccine development, clinical trials, and research is t...
Memory T cells are heterogeneous in phenotype and function. In this issue of Immunity, Newell et al....
The adaptive immune response meets the needs of the organism to generate effector cells capable of c...
Understanding heterogeneity in adaptive immune responses is essential to dissect pathways of memory ...
Cellular immunity has an inherent high level of functional heterogeneity. Capturing the full spectru...
SummaryCytotoxic CD8+ T lymphocytes directly kill infected or aberrant cells and secrete proinflamma...
Variation in protein expression is a feature of all cell populations. Using T cell subsets as a proo...
SummarySingle-cell analysis technologies such as mass cytometry allow for measurements of cellular h...
The potency of cellular immune responses strongly depends on T cell avidity to antigen. Yet, functio...
Our body is composed of a diverse set of cells that together perform numerous functions in a highly ...
This thesis describes the research that was performed to unravel the function and development of hum...
SummaryThe killing of antigen-bearing cells by clonal populations of cytotoxic T lymphocytes (CTLs) ...
Activated CD8+ T cells can differentiate into transient effector cells or long-lived memory cells. I...
Phenotypic and functional heterogeneity are the hallmarks of effector and memory T cells. Upon antig...
The probabilistic expression of cytokine genes in differentiated T helper (Th) cell populations rema...
An important aspect of immune monitoring for vaccine development, clinical trials, and research is t...
Memory T cells are heterogeneous in phenotype and function. In this issue of Immunity, Newell et al....
The adaptive immune response meets the needs of the organism to generate effector cells capable of c...
Understanding heterogeneity in adaptive immune responses is essential to dissect pathways of memory ...
Cellular immunity has an inherent high level of functional heterogeneity. Capturing the full spectru...
SummaryCytotoxic CD8+ T lymphocytes directly kill infected or aberrant cells and secrete proinflamma...
Variation in protein expression is a feature of all cell populations. Using T cell subsets as a proo...
SummarySingle-cell analysis technologies such as mass cytometry allow for measurements of cellular h...
The potency of cellular immune responses strongly depends on T cell avidity to antigen. Yet, functio...
Our body is composed of a diverse set of cells that together perform numerous functions in a highly ...
This thesis describes the research that was performed to unravel the function and development of hum...
SummaryThe killing of antigen-bearing cells by clonal populations of cytotoxic T lymphocytes (CTLs) ...
Activated CD8+ T cells can differentiate into transient effector cells or long-lived memory cells. I...
Phenotypic and functional heterogeneity are the hallmarks of effector and memory T cells. Upon antig...
The probabilistic expression of cytokine genes in differentiated T helper (Th) cell populations rema...
An important aspect of immune monitoring for vaccine development, clinical trials, and research is t...