AbstractIn zebrafish, the endoderm originates at the blastula stage from the most marginal blastomeres. Through a series of complex morphogenetic movements and differentiation events, the endodermal germ layer gives rise to the epithelial lining of the digestive tract as well as its associated organs such as the liver, pancreas, and swim bladder. How endodermal cells differentiate into distinct cell types such as hepatocytes or endocrine and exocrine pancreatic cells remains a major question. In a forward genetic screen for genes regulating endodermal organ development, we identified mutations at the shiri locus that cause defects in the development of a number of endodermal organs including the liver and pancreas. Detailed phenotypic analy...
AbstractThe gastrulating vertebrate embryo develops three germlayers: ectoderm, mesoderm, and endode...
In vertebrates, the embryonic dorsoventral asymmetry is regulated by the bone morphogenetic proteins...
The endoderm is the innermost embryonic germ layer, and in zebrafish, it gives rise to the lining of...
AbstractBackground: Several potentially important regulators of vertebrate endoderm development have...
During embryonic development in vertebrates, the endoderm becomes patterned along the anteroposterio...
AbstractThe cellular and molecular mechanisms that regulate endoderm development in vertebrates have...
AbstractAlthough the development of the digestive system of humans and vertebrate model organisms ha...
The pancreas is located below the liver and adjacent to the small intestine where it connects to the...
The digestive tract and its accessory organs - liver, pancreas, and the inner lining of the swim bla...
The regulatory signaling pathways crucial during embryonic development seem to play key roles in adu...
The vertebrate endoderm makes major contributions to the respiratory and gastrointestinal tracts and...
The gastrulating vertebrate embryo develops three germlayers: ectoderm, mesoderm, and endoderm. Zebr...
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas gen...
The formation of the vertebrate body plan begins with the segregation of undifferentiated mass of ce...
AbstractThe zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is p...
AbstractThe gastrulating vertebrate embryo develops three germlayers: ectoderm, mesoderm, and endode...
In vertebrates, the embryonic dorsoventral asymmetry is regulated by the bone morphogenetic proteins...
The endoderm is the innermost embryonic germ layer, and in zebrafish, it gives rise to the lining of...
AbstractBackground: Several potentially important regulators of vertebrate endoderm development have...
During embryonic development in vertebrates, the endoderm becomes patterned along the anteroposterio...
AbstractThe cellular and molecular mechanisms that regulate endoderm development in vertebrates have...
AbstractAlthough the development of the digestive system of humans and vertebrate model organisms ha...
The pancreas is located below the liver and adjacent to the small intestine where it connects to the...
The digestive tract and its accessory organs - liver, pancreas, and the inner lining of the swim bla...
The regulatory signaling pathways crucial during embryonic development seem to play key roles in adu...
The vertebrate endoderm makes major contributions to the respiratory and gastrointestinal tracts and...
The gastrulating vertebrate embryo develops three germlayers: ectoderm, mesoderm, and endoderm. Zebr...
sonic hedgehog (shh) is expressed in anterior endoderm, where it is required to repress pancreas gen...
The formation of the vertebrate body plan begins with the segregation of undifferentiated mass of ce...
AbstractThe zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is p...
AbstractThe gastrulating vertebrate embryo develops three germlayers: ectoderm, mesoderm, and endode...
In vertebrates, the embryonic dorsoventral asymmetry is regulated by the bone morphogenetic proteins...
The endoderm is the innermost embryonic germ layer, and in zebrafish, it gives rise to the lining of...