AbstractInsulin secretion is thought principally to be regulated by blood glucose concentration. Three recent studies emphasise the additional importance of fatty acids as regulators of insulin secretion, and demonstrate the involvement of a novel G protein-coupled receptor
SummaryExcessive secretion of glucagon is a major contributor to the development of diabetic hypergl...
Insulin secretion by pancreatic β-cells is primarily regulated by glucose; however, hormones and add...
Pancreatic beta-cells regulate blood glucose by secreting insulin in response to nutrients. The deve...
AbstractInsulin secretion is thought principally to be regulated by blood glucose concentration. Thr...
G protein-coupled receptors have been well described to contribute to the regulation of glucose-stim...
G protein-coupled receptor 40 (GPR40)/free fatty acid 1 (FFA1) is a G protein-coupled receptor invol...
pressed in pancreatic -cells and is activated by long-chain fatty acids. Gene deletion studies have ...
It is well known that free fatty acids (FFAs) play a central role in insulin resistance. However, in...
Aims/hypothesis: Activation of the G protein-coupled receptor (GPR)40 by long-chain fatty acids pote...
Phospholipase Cβ (PLCβ) is a membrane-associated enzyme activated by membrane receptors, especially ...
The epidemic of type 2 diabetes and impaired glucose tolerance is one of the main causes of morbidit...
Free fatty acids (FFA) have generally been proposed to regulate pancreatic insulin release by an int...
AIMS/HYPOTHESIS: Activation of the G protein-coupled receptor (GPR)40 by long-chain fatty acids pote...
SummaryGlucagon plays an important role in glucose homeostasis by regulating hepatic glucose output ...
SummaryObesity is typically associated with elevated levels of free fatty acids (FFAs) and is linked...
SummaryExcessive secretion of glucagon is a major contributor to the development of diabetic hypergl...
Insulin secretion by pancreatic β-cells is primarily regulated by glucose; however, hormones and add...
Pancreatic beta-cells regulate blood glucose by secreting insulin in response to nutrients. The deve...
AbstractInsulin secretion is thought principally to be regulated by blood glucose concentration. Thr...
G protein-coupled receptors have been well described to contribute to the regulation of glucose-stim...
G protein-coupled receptor 40 (GPR40)/free fatty acid 1 (FFA1) is a G protein-coupled receptor invol...
pressed in pancreatic -cells and is activated by long-chain fatty acids. Gene deletion studies have ...
It is well known that free fatty acids (FFAs) play a central role in insulin resistance. However, in...
Aims/hypothesis: Activation of the G protein-coupled receptor (GPR)40 by long-chain fatty acids pote...
Phospholipase Cβ (PLCβ) is a membrane-associated enzyme activated by membrane receptors, especially ...
The epidemic of type 2 diabetes and impaired glucose tolerance is one of the main causes of morbidit...
Free fatty acids (FFA) have generally been proposed to regulate pancreatic insulin release by an int...
AIMS/HYPOTHESIS: Activation of the G protein-coupled receptor (GPR)40 by long-chain fatty acids pote...
SummaryGlucagon plays an important role in glucose homeostasis by regulating hepatic glucose output ...
SummaryObesity is typically associated with elevated levels of free fatty acids (FFAs) and is linked...
SummaryExcessive secretion of glucagon is a major contributor to the development of diabetic hypergl...
Insulin secretion by pancreatic β-cells is primarily regulated by glucose; however, hormones and add...
Pancreatic beta-cells regulate blood glucose by secreting insulin in response to nutrients. The deve...
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