Calcium and pancreatic alpha cells in metabolism

Note:Fifty years of sustained effort by numerous workers have not sufficed to furnish a complete understanding of the problem of carbohydrate metabolism or its most prevalent disturbance, diabetes mellitus. Although many factors are still unexplained, this disease is, however, adequately dealt with by modern therapeutic . Until thirty years ago, diabetes mellitus was a hopeless disease; nowadays, diabetics, with insulin treatment, enjoy a nearly normal lite.[...] This work is complemented, first, by a survey of the evidence in favor of a hyperglycemic hormone of the Alpha cells of the pancreas and, second, by discussions on the possible role of pancreatic Alpha cells in metabolism