In recognition of the first protein kinase structure that was solved 25 years ago, we review the history of the Structural Kinome. What did we learn prior to that first structure of the PKA catalytic subunit, what have we learned since the structure was solved, and what are our remaining challenges for the future
AbstractBackground: Control of intracellular events by protein phosphorylation is promoted by specif...
led to a better understanding of both the complexity and the subtlety of PKA signaling, and point th...
Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating targeted ...
In recognition of the first protein kinase structure that was solved 25 years ago, we review the his...
Eukaryotic protein kinases evolved as a family of highly dynamic molecules with strictly organized i...
The eukaryotic protein kinases (ePKs) constitute one of the largest families of enzymes encoded by e...
AbstractProtein kinases catalyse phospho transfer reactions from ATP to serine, threonine or tyrosin...
AbstractProtein kinases operate in a large number of distinct signaling pathways, where the tight re...
The catalytic activity of protein kinases is usually tightly controlled by posttranslational modific...
AbstractProtein structure determination of soluble globular protein domains has developed into an ef...
<div><p>The protein kinase family is large and important, but it is only one family in a larger supe...
Protein kinases provide a platform for the integration of signal transduction networks. A key featur...
<div><p>Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating t...
AbstractUnderstanding how phosphoryl transfer is accomplished by kinases, a ubiquitous group of enzy...
All research conducted at EMBL-EBI under the supervision of Dr. Pedro Beltrao. Work on the PhD proje...
AbstractBackground: Control of intracellular events by protein phosphorylation is promoted by specif...
led to a better understanding of both the complexity and the subtlety of PKA signaling, and point th...
Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating targeted ...
In recognition of the first protein kinase structure that was solved 25 years ago, we review the his...
Eukaryotic protein kinases evolved as a family of highly dynamic molecules with strictly organized i...
The eukaryotic protein kinases (ePKs) constitute one of the largest families of enzymes encoded by e...
AbstractProtein kinases catalyse phospho transfer reactions from ATP to serine, threonine or tyrosin...
AbstractProtein kinases operate in a large number of distinct signaling pathways, where the tight re...
The catalytic activity of protein kinases is usually tightly controlled by posttranslational modific...
AbstractProtein structure determination of soluble globular protein domains has developed into an ef...
<div><p>The protein kinase family is large and important, but it is only one family in a larger supe...
Protein kinases provide a platform for the integration of signal transduction networks. A key featur...
<div><p>Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating t...
AbstractUnderstanding how phosphoryl transfer is accomplished by kinases, a ubiquitous group of enzy...
All research conducted at EMBL-EBI under the supervision of Dr. Pedro Beltrao. Work on the PhD proje...
AbstractBackground: Control of intracellular events by protein phosphorylation is promoted by specif...
led to a better understanding of both the complexity and the subtlety of PKA signaling, and point th...
Eukaryotic protein kinases (EPKs) regulate numerous signaling processes by phosphorylating targeted ...
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