Human platelets release α-6-L-fucosyltransferase upon activation

AbstractPreviously we have shown that human platelets release α-6-L-fucosyltransferase (EC 2.4.1.68) during coagulation of blood [(1987) Glycoconjugate J. 4, 43–49]. Here we report that agonists which induce platelet aggregation bring about release of the enzyme. In quantitative terms the release of α-6-L-fucosyltransferase by washed, aggregated platelets was very similar to that occurring during blood coagulation