0274: Cardiac involvement in Behcet’s disease

BackgroundBehcet’s disease is a multisystem disorder and classified as « vasculitic syndrome with a wide variety of clinical manifestations. » Cardiac involvement is very rare but can occur with different presentations.ObjectiveTo analyze the clinical characteristics of Behcet’s disease with cardiac involvement.MethodsPatients diagnosed as Behcet’s disease with cardiac involvement in our Hospital from 1998 to 2013 were included in this analysis. The clinical characteristics of these patients were studied retrospectively.ResultsEighteen cardiac manifestations observed in 13 patients with Behçet’s disease are reported. 11 (84.6%) patients were male, with a mean (±SD) age at BD diagnosis of 34.2±9.9 years. Cardiac involvement was the first feature of BD in 9 (69.23%) patients. Cardiac involvement included ST-elevation myocardial infarction (4 cases, 22.22%), stable angina (1case, 5.5%), right heart failure (2 cases 11.1%), pericardial effusion (4 cases, 22.22%), intracardiac thrombus (2 cases, 11.1%), pulmonary artery hypertension (4 cases, 22.22%) (Consecutive to pulmonary embolism in three cases) and valvular disease (mitral insufficiency) (1 case, 5.5%). After a median follow-up of 59.73 (0-180) months, 2 patients had died (directly related to cardiac involvement).ConclusionsThe manifestation of cardiac involvement in Behcet’s disease is various. The involvement of pulmonary artery is an independent correlative factor of mortality. Cardiologists should always bear in mind potential threats of (a) symptomatic cardiovascular involvement in BD