SummaryParkin is an E3 ubiquitin ligase, mutations in which are responsible for autosomal recessive juvenile parkinsonism. Recently, several structures of Parkin have been solved, revealing its serpentine shape and modes of auto-inhibition
Mutations in the park2 gene, encoding the RING-inBetweenRING-RING E3 ubiquitin ligase parkin, cause ...
Parkinson's disease (PD) is the second most common neurodegenerative disease, and is characterized b...
Autosomal recessive mutations in the Parkin gene cause Parkinson's disease. Parkin encodes an ubiqui...
SummaryParkin is an E3 ubiquitin ligase, mutations in which are responsible for autosomal recessive ...
The PARK2 gene is mutated in 50% of autosomal recessive juvenile parkinsonism (ARJP) cases. It encod...
Parkinson’s disease (PD), the second most common neurodegenerative disease in men. Parkin is an E3 u...
Mutations in the park2 gene, encoding the RING-inBetweenRING-RING E3 ubiquitin ligase parkin, cause ...
Parkinson’s disease (PD) is the second most common neurodegenerative disease. Around 10% of PD cases...
RING-between-RING (RBR) E3 ligases are a class of ubiquitin ligases distinct from RING or HECT E3 li...
Mutations in the gene encoding parkin, an E3-ubiquitin ligase, result in 50% of Autosomal Recessive ...
The PARK2 gene is mutated in 50 % of autosomal recessive juvenile parkinsonism (ARJP) cases. It enco...
Missense mutations in park2, encoding the parkin protein, account for approximately 50% of autosomal...
Post-translational modification of proteins by ubiquitin is a central regulatory process in all euk...
Parkin belongs to a class of multiple RING domain proteins designated as RBR (RING, in between RING,...
Parkin is an E3-ubiquitin ligase belonging to the RBR (RING-InBetweenRING-RING family), and is invol...
Mutations in the park2 gene, encoding the RING-inBetweenRING-RING E3 ubiquitin ligase parkin, cause ...
Parkinson's disease (PD) is the second most common neurodegenerative disease, and is characterized b...
Autosomal recessive mutations in the Parkin gene cause Parkinson's disease. Parkin encodes an ubiqui...
SummaryParkin is an E3 ubiquitin ligase, mutations in which are responsible for autosomal recessive ...
The PARK2 gene is mutated in 50% of autosomal recessive juvenile parkinsonism (ARJP) cases. It encod...
Parkinson’s disease (PD), the second most common neurodegenerative disease in men. Parkin is an E3 u...
Mutations in the park2 gene, encoding the RING-inBetweenRING-RING E3 ubiquitin ligase parkin, cause ...
Parkinson’s disease (PD) is the second most common neurodegenerative disease. Around 10% of PD cases...
RING-between-RING (RBR) E3 ligases are a class of ubiquitin ligases distinct from RING or HECT E3 li...
Mutations in the gene encoding parkin, an E3-ubiquitin ligase, result in 50% of Autosomal Recessive ...
The PARK2 gene is mutated in 50 % of autosomal recessive juvenile parkinsonism (ARJP) cases. It enco...
Missense mutations in park2, encoding the parkin protein, account for approximately 50% of autosomal...
Post-translational modification of proteins by ubiquitin is a central regulatory process in all euk...
Parkin belongs to a class of multiple RING domain proteins designated as RBR (RING, in between RING,...
Parkin is an E3-ubiquitin ligase belonging to the RBR (RING-InBetweenRING-RING family), and is invol...
Mutations in the park2 gene, encoding the RING-inBetweenRING-RING E3 ubiquitin ligase parkin, cause ...
Parkinson's disease (PD) is the second most common neurodegenerative disease, and is characterized b...
Autosomal recessive mutations in the Parkin gene cause Parkinson's disease. Parkin encodes an ubiqui...
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