AbstractCurrent models for epigenetic gene silencing envision a static relationship between histone modifications and transcription. However, evidence for nucleosome mobility and replacement favors a dynamic model that may explain phenomena ranging from variegation to the neural restriction of Rett syndrome
Chromosomal regions can adopt stable and heritable alternative states resulting in bistable gene exp...
The development of an adult organism from a fertilized egg is accompanied by the generation of some ...
AbstractThe dynamic packaging of DNA into chromatin is a key determinant of eukaryotic gene regulati...
Epigenetics is the study of heritable changes in gene expression that do not involve changes in the ...
SummaryChromosomal regions can adopt stable and heritable alternative states resulting in bistable g...
The human genome consists of over 3 billion nucleotides and would be around 2 meters long if uncoile...
SummaryThe nucleosome represents a mechanical barrier to transcription that operates as a general re...
In eukaryotic cells, the genome is packed into fundamental units called nucleosomes, where 147 base ...
A core assumption in chromatin biology is that nucleosomes store and transmit epigenetic memory of g...
The gene transcription patterns are regulated in response to extracellular stimuli and intracellular...
\noindent \textbf{Background} \\ The activity of a single gene is influenced by the composition of ...
The genomic positions of nucleosomes are a defining feature of the cell's epigenomic state, but sign...
International audienceAbstract In eukaryotes, many stable and heritable phenotypes arise from the sa...
Combinatorial effects of epigenetic modifications on transcription activity have been proposed as “h...
Combinatorial effects of epigenetic modifications on transcription activity have been proposed as "h...
Chromosomal regions can adopt stable and heritable alternative states resulting in bistable gene exp...
The development of an adult organism from a fertilized egg is accompanied by the generation of some ...
AbstractThe dynamic packaging of DNA into chromatin is a key determinant of eukaryotic gene regulati...
Epigenetics is the study of heritable changes in gene expression that do not involve changes in the ...
SummaryChromosomal regions can adopt stable and heritable alternative states resulting in bistable g...
The human genome consists of over 3 billion nucleotides and would be around 2 meters long if uncoile...
SummaryThe nucleosome represents a mechanical barrier to transcription that operates as a general re...
In eukaryotic cells, the genome is packed into fundamental units called nucleosomes, where 147 base ...
A core assumption in chromatin biology is that nucleosomes store and transmit epigenetic memory of g...
The gene transcription patterns are regulated in response to extracellular stimuli and intracellular...
\noindent \textbf{Background} \\ The activity of a single gene is influenced by the composition of ...
The genomic positions of nucleosomes are a defining feature of the cell's epigenomic state, but sign...
International audienceAbstract In eukaryotes, many stable and heritable phenotypes arise from the sa...
Combinatorial effects of epigenetic modifications on transcription activity have been proposed as “h...
Combinatorial effects of epigenetic modifications on transcription activity have been proposed as "h...
Chromosomal regions can adopt stable and heritable alternative states resulting in bistable gene exp...
The development of an adult organism from a fertilized egg is accompanied by the generation of some ...
AbstractThe dynamic packaging of DNA into chromatin is a key determinant of eukaryotic gene regulati...
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