MicroRNA Gene Regulatory Pathways in the Establishment and Maintenance of ESC Identity
- Martinez, Natalia J.
- Gregory, Richard I.
Publication date
July 2010
DOI Publisher
Elsevier Inc. ISSN
1934-5909 Citation count (estimate)
105Abstract
Understanding the molecular foundations of embryonic stem cell (ESC) self-renewal and pluripotency will facilitate therapeutic exploitation of these remarkable cells. Here we discuss the emerging roles of microRNAs in the establishment and maintenance of ESC identity and summarize our current understanding of the mechanisms controlling microRNA expression and function in ESCs
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