AbstractProteolytic fragments of various components of the extracellular matrix exhibit antiangiogenic activity via interaction with endothelial cell surface integrins. Kalluri and coworkers (Hamano et al., 2003; this issue of Cancer Cell) use gene-targeted mice to show a physiological role for a carboxy-terminal fragment of collagen IV in the regulation of tumor angiogenesis
Three-dimensional tumor growth is dependent on the perpetual recruitment of host blood vessels to th...
AbstractA mutant Raf-1 gene loaded onto nanoparticles, delivered to tumor vasculature with an integr...
Integrins are a family of cell-extracellular matrix adhesion molecules that play important roles in ...
Proteolytic fragments of various components of the extracellular matrix exhibit antiangiogenic activ...
AbstractWe demonstrate a physiological role for tumstatin, a cleavage fragment of the α3 chain of ty...
AbstractMice carrying a targeted deletion of the signaling portion of the integrin β4 subunit displa...
The process of angiogenesis involves a complex set of cell-cell and cell-extracellular matrix (ECM) ...
AbstractMice carrying a targeted deletion of the signaling portion of the integrin β4 subunit displa...
Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in ...
Tumor angiogenesis is an essential step in tumor progression and metastasis formation. Suppression o...
AbstractThe interactions between integrins and the extracellular matrix have been identified as impo...
In order to grow beyond minimal size and to metastasize, tumors need to induce the growth of new blo...
peer reviewedAnti-angiogenic treatments against alphavbeta3-integrin fail to block tumour growth in ...
AbstractAngiogenic defects in Id mutant mice inhibit the growth of tumor xenografts, providing a gen...
Anti-angiogenic treatments against alphavbeta3-integrin fail to block tumour growth in the long term...
Three-dimensional tumor growth is dependent on the perpetual recruitment of host blood vessels to th...
AbstractA mutant Raf-1 gene loaded onto nanoparticles, delivered to tumor vasculature with an integr...
Integrins are a family of cell-extracellular matrix adhesion molecules that play important roles in ...
Proteolytic fragments of various components of the extracellular matrix exhibit antiangiogenic activ...
AbstractWe demonstrate a physiological role for tumstatin, a cleavage fragment of the α3 chain of ty...
AbstractMice carrying a targeted deletion of the signaling portion of the integrin β4 subunit displa...
The process of angiogenesis involves a complex set of cell-cell and cell-extracellular matrix (ECM) ...
AbstractMice carrying a targeted deletion of the signaling portion of the integrin β4 subunit displa...
Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in ...
Tumor angiogenesis is an essential step in tumor progression and metastasis formation. Suppression o...
AbstractThe interactions between integrins and the extracellular matrix have been identified as impo...
In order to grow beyond minimal size and to metastasize, tumors need to induce the growth of new blo...
peer reviewedAnti-angiogenic treatments against alphavbeta3-integrin fail to block tumour growth in ...
AbstractAngiogenic defects in Id mutant mice inhibit the growth of tumor xenografts, providing a gen...
Anti-angiogenic treatments against alphavbeta3-integrin fail to block tumour growth in the long term...
Three-dimensional tumor growth is dependent on the perpetual recruitment of host blood vessels to th...
AbstractA mutant Raf-1 gene loaded onto nanoparticles, delivered to tumor vasculature with an integr...
Integrins are a family of cell-extracellular matrix adhesion molecules that play important roles in ...
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