149 Assessment of left ventricular volumes and function by 3D real-time transthoracic echocardiography in children: Comparison of Qlab and Tomtec full volume reconstruction

BackgroundThree-dimensional echocardiography (3DE) allows calculation of ventricular volumes without geometric assumption on the ventricular shape. Real Time 3DE is validated to evaluate left ventricular (LV) volumes and function in adults. Accuracy of the two full volume reconstruction softwares Tomtec and Qlab have not been yet studied in children.AimTo apply 3DE in a normal pediatric population and to compare the left ventricular volumes measurements between these two analysing softwares.MethodsFifty pediatric patients (median age 10 years) with normal cardiac anatomy and function were included. 3D transthoracic echocardiography was performed with the X4-2 or X7-2 matrix probe (ie33, Philips Medical Systems, Andover, MA). Off-line left ventricular (LV) volume analysis was performed with QLAB 6.0 (Semi-automated border detection with biplane projections) and TomTec 4D LV analysis (primarily manual tracking with triplane projections and semiautomated border detection).ResultsFeasibility was 94% for both softwares. Measurements of LV stroke volume, end-diastolic and end-systolic were strongly correlated (r=0.96; p<0.0001). LV ejection fraction measurements were well correlated between the 2 methods (r=0.78; p <0,0001). Mean LV ejection fraction difference was 3.9% +/- 8. No difference was found between Qlab and Tomtec observer variability. Nevertheless Tomtec inter Observer variability tends to be higher. The analysis time was shorter with QLAB (5 +/- 2 min vs. 6 +/- 3, p