Despite their fundamental role in host defense, many components of epithelial and endothelial tight junctions serve as viral receptors. In this issue of Cell Host & Microbe, Antar et al. (2009) provide striking in vivo evidence that the broadly expressed reovirus receptor JAM-A plays a specific role in reovirus dissemination
Entry of reovirus virions has been well studied in several tissue culture systems. After attachment ...
Junctional adhesion molecules (JAMs) are a family of adhesion molecules localized at the tight junct...
Reovirus attachment to cells is mediated by the binding of viral attachment protein sigma 1 to junct...
Despite their fundamental role in host defense, many components of epithelial and endothelial tight ...
SummaryDiverse families of viruses bind immunoglobulin superfamily (IgSF) proteins located in tight ...
ABSTRACT Bloodstream spread is a critical step in the pathogenesis of many viruses. However, mechani...
AbstractVirus attachment to cells plays an essential role in viral tropism and disease. Reovirus ser...
Tight junctions (TJs) are highly specialized membrane domains involved in many important cellular pr...
SummaryNeurotropic viruses, including mammalian reovirus, must disseminate from an initial site of r...
Viral infection is an intricate process that requires the concerted action of both viral and host ce...
AbstractCertain virus receptors are sequestered on the basolateral surface of polarized epithelial c...
Most viruses infect their hosts by crossing the mucosal surfaces of the respiratory, gastrointestina...
The coxsackievirus and adenovirus receptor (CAR) mediates viral attachment and infection, but its ph...
SummaryGroup B coxsackieviruses (CVBs) must cross the epithelium as they initiate infection, but the...
AbstractAdenovirus binds its receptor (CAR), enters cells, and replicates. It must then escape to th...
Entry of reovirus virions has been well studied in several tissue culture systems. After attachment ...
Junctional adhesion molecules (JAMs) are a family of adhesion molecules localized at the tight junct...
Reovirus attachment to cells is mediated by the binding of viral attachment protein sigma 1 to junct...
Despite their fundamental role in host defense, many components of epithelial and endothelial tight ...
SummaryDiverse families of viruses bind immunoglobulin superfamily (IgSF) proteins located in tight ...
ABSTRACT Bloodstream spread is a critical step in the pathogenesis of many viruses. However, mechani...
AbstractVirus attachment to cells plays an essential role in viral tropism and disease. Reovirus ser...
Tight junctions (TJs) are highly specialized membrane domains involved in many important cellular pr...
SummaryNeurotropic viruses, including mammalian reovirus, must disseminate from an initial site of r...
Viral infection is an intricate process that requires the concerted action of both viral and host ce...
AbstractCertain virus receptors are sequestered on the basolateral surface of polarized epithelial c...
Most viruses infect their hosts by crossing the mucosal surfaces of the respiratory, gastrointestina...
The coxsackievirus and adenovirus receptor (CAR) mediates viral attachment and infection, but its ph...
SummaryGroup B coxsackieviruses (CVBs) must cross the epithelium as they initiate infection, but the...
AbstractAdenovirus binds its receptor (CAR), enters cells, and replicates. It must then escape to th...
Entry of reovirus virions has been well studied in several tissue culture systems. After attachment ...
Junctional adhesion molecules (JAMs) are a family of adhesion molecules localized at the tight junct...
Reovirus attachment to cells is mediated by the binding of viral attachment protein sigma 1 to junct...