The intestinal mucosa harbors trillions of commensal bacteria that provide the host with nutrients and contribute to resistance to infections but, in certain instances, also potentiate the generation of proinflammatory cells. Recent studies unveil how this delicate balance is achieved and how it can be manipulated for therapeutic purposes
Regulatory T cells (Tregs) that express the transcription factor Foxp3 are critical for regulating i...
Omenn syndrome (OS) is caused by hypomorphic Rag mutations and characterized by a profound immunodef...
SummaryInteractions between the microbiota and distal gut are fundamental determinants of human heal...
Summary: Antibiotic-induced dysbiosis is a key factor predisposing intestinal infection by Clostridi...
Mucosal tolerance is central to efficient gastrointestinal tract function, tolerating food and comme...
The intestinal mucosa harbors trillions of commensal bacteria that provide the host with nutrients a...
A complex partnership between the host and the vast intestinal microbial ecosystem serves numerous b...
Quantitative and qualitative aspects of commensal bacteria determine the active and quiescent status...
BACKGROUND AND AIMS: Reg3 lectins are antimicrobial peptides at mucosal surfaces of the gut, whose e...
International audienceGut microbiota has a fundamental role in the energy homeostasis of the host an...
To maintain intestinal health, the immune system must faithfully respond to antigens from pathogenic...
P-glycoprotein (P-gp) protects the mammalian intestinal epithelium by effluxing toxins from the epit...
SummaryThe intestinal tract is in intimate contact with the commensal microflora. Nevertheless, how ...
International audienceBACKGROUND & AIMS: Paneth cell dysfunction causes deficiencies in intestinal C...
Decreases in short-chain-fatty-acids (SCFAs) are linked to inflammatory bowel disease (IBD). Yet, th...
Regulatory T cells (Tregs) that express the transcription factor Foxp3 are critical for regulating i...
Omenn syndrome (OS) is caused by hypomorphic Rag mutations and characterized by a profound immunodef...
SummaryInteractions between the microbiota and distal gut are fundamental determinants of human heal...
Summary: Antibiotic-induced dysbiosis is a key factor predisposing intestinal infection by Clostridi...
Mucosal tolerance is central to efficient gastrointestinal tract function, tolerating food and comme...
The intestinal mucosa harbors trillions of commensal bacteria that provide the host with nutrients a...
A complex partnership between the host and the vast intestinal microbial ecosystem serves numerous b...
Quantitative and qualitative aspects of commensal bacteria determine the active and quiescent status...
BACKGROUND AND AIMS: Reg3 lectins are antimicrobial peptides at mucosal surfaces of the gut, whose e...
International audienceGut microbiota has a fundamental role in the energy homeostasis of the host an...
To maintain intestinal health, the immune system must faithfully respond to antigens from pathogenic...
P-glycoprotein (P-gp) protects the mammalian intestinal epithelium by effluxing toxins from the epit...
SummaryThe intestinal tract is in intimate contact with the commensal microflora. Nevertheless, how ...
International audienceBACKGROUND & AIMS: Paneth cell dysfunction causes deficiencies in intestinal C...
Decreases in short-chain-fatty-acids (SCFAs) are linked to inflammatory bowel disease (IBD). Yet, th...
Regulatory T cells (Tregs) that express the transcription factor Foxp3 are critical for regulating i...
Omenn syndrome (OS) is caused by hypomorphic Rag mutations and characterized by a profound immunodef...
SummaryInteractions between the microbiota and distal gut are fundamental determinants of human heal...
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