Signal transduction cascades, such as Hedgehog (Hh) signaling, are potentially important targets for new drugs. A new study in this issue of Cell Metabolism (Suh et al., 2006) identifies hedgehog signaling in the formation of the Drosophila fly body and in mammalian adipogenesis
International audienceHuman stem cells are powerful tools by which to investigate molecular mechanis...
The Hedgehog signaling pathway regulates many processes during embryogenesis and the homeostasis of ...
The Hedgehog signaling pathway regulates many processes during embryogenesis and the homeostasis of ...
SummaryOver 1 billion people are estimated to be overweight, placing them at risk for diabetes, card...
Over 1 billion people are estimated to be overweight, placing them at risk for diabetes, cardiovascu...
Over 1 billion people are estimated to be overweight, placing them at risk for diabetes, cardiovascu...
International audienceMorphogenes, abundantly described during embryogenesis have recently emerged a...
Hedgehog (Hh) shape up development by playing important role in signaling, and thereby controlling g...
The biological functions of hedgehog signaling encompass not only its well-defined role in embryonic...
AbstractBy coupling to cholesterol, Hedgehog can be anchored to the cells where it is made, yet to a...
Developmental genes are essential in the formation and function of adipose tissue and muscle. In thi...
The physiological response to environmental cues involves complex interorgan communication via endoc...
SummaryBackgroundThe Hippo tumor-suppressor pathway has emerged as a key signaling pathway that cont...
SummaryDiabetes, obesity, and cancer affect upward of 15% of the world’s population. Interestingly, ...
Abstract Signaling pathways direct organogenesis, often through concentration-dependent effects on c...
International audienceHuman stem cells are powerful tools by which to investigate molecular mechanis...
The Hedgehog signaling pathway regulates many processes during embryogenesis and the homeostasis of ...
The Hedgehog signaling pathway regulates many processes during embryogenesis and the homeostasis of ...
SummaryOver 1 billion people are estimated to be overweight, placing them at risk for diabetes, card...
Over 1 billion people are estimated to be overweight, placing them at risk for diabetes, cardiovascu...
Over 1 billion people are estimated to be overweight, placing them at risk for diabetes, cardiovascu...
International audienceMorphogenes, abundantly described during embryogenesis have recently emerged a...
Hedgehog (Hh) shape up development by playing important role in signaling, and thereby controlling g...
The biological functions of hedgehog signaling encompass not only its well-defined role in embryonic...
AbstractBy coupling to cholesterol, Hedgehog can be anchored to the cells where it is made, yet to a...
Developmental genes are essential in the formation and function of adipose tissue and muscle. In thi...
The physiological response to environmental cues involves complex interorgan communication via endoc...
SummaryBackgroundThe Hippo tumor-suppressor pathway has emerged as a key signaling pathway that cont...
SummaryDiabetes, obesity, and cancer affect upward of 15% of the world’s population. Interestingly, ...
Abstract Signaling pathways direct organogenesis, often through concentration-dependent effects on c...
International audienceHuman stem cells are powerful tools by which to investigate molecular mechanis...
The Hedgehog signaling pathway regulates many processes during embryogenesis and the homeostasis of ...
The Hedgehog signaling pathway regulates many processes during embryogenesis and the homeostasis of ...