DNA repair: RAD alert

  • Ivanov, Eugene L.
  • Haber, James E.
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Publication date
August 1997
Publisher
Elsevier BV
ISSN
0960-9822
Citation count (estimate)
35

Abstract

AbstractMammalian homologues of two important yeast genes involved in DNA double-strand break repair and recombination, RAD51 and RAD54, have been isolated. Knock-out mutations of the genes in mice reveal both reassuring similarities to, and surprising differences from, the analogous mutant phenotypes in yeast

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