AbstractMammalian homologues of two important yeast genes involved in DNA double-strand break repair and recombination, RAD51 and RAD54, have been isolated. Knock-out mutations of the genes in mice reveal both reassuring similarities to, and surprising differences from, the analogous mutant phenotypes in yeast
<div><p>Systems for the repair of DNA double-strand breaks (DSBs) are necessary to maintain genome i...
The aim of this thesis is to investigate the function of a number of genes involved in mammalian DN...
Regulation of the repair of DNA double-strand breaks by homologous recombination is extremely import...
AbstractMammalian homologues of two important yeast genes involved in DNA double-strand break repair...
AbstractBackground: Homologous recombination is of eminent importance both in germ cells, to generat...
AbstractDouble-strand DNA break (DSB) repair by homologous recombination occurs through the RAD52 pa...
In haploid rad52 Saccharomyces cerevisiae strains unable to undergo homologous recombination, a chro...
DNA double-strand breaks (DSBs) are a major form of DNA damage, and its accurate repair is critical ...
AbstractIn this work we report that the Saccharomyces cerevisiae RAD9, RAD24, RAD17, MEC1, MEC3 and ...
textabstractDouble-strand DNA break (DSB) repair by homologous recombination occurs through the RAD5...
Chromosomal translocations are a primary biological response to ionizing radiation (IR) exposure, an...
All organisms are composed of cells and the cell's nucleus contains DNA. The induction of DNA damage...
Chromosomal translocations are a primary biological response to ionizing radiation (IR) exposure, an...
Homologous recombination (HR) and nonhomologous end-joining (NHEJ) are mechanistically distinct DNA ...
Homologous recombination is of major importance for the prevention of genomic instability during chr...
<div><p>Systems for the repair of DNA double-strand breaks (DSBs) are necessary to maintain genome i...
The aim of this thesis is to investigate the function of a number of genes involved in mammalian DN...
Regulation of the repair of DNA double-strand breaks by homologous recombination is extremely import...
AbstractMammalian homologues of two important yeast genes involved in DNA double-strand break repair...
AbstractBackground: Homologous recombination is of eminent importance both in germ cells, to generat...
AbstractDouble-strand DNA break (DSB) repair by homologous recombination occurs through the RAD52 pa...
In haploid rad52 Saccharomyces cerevisiae strains unable to undergo homologous recombination, a chro...
DNA double-strand breaks (DSBs) are a major form of DNA damage, and its accurate repair is critical ...
AbstractIn this work we report that the Saccharomyces cerevisiae RAD9, RAD24, RAD17, MEC1, MEC3 and ...
textabstractDouble-strand DNA break (DSB) repair by homologous recombination occurs through the RAD5...
Chromosomal translocations are a primary biological response to ionizing radiation (IR) exposure, an...
All organisms are composed of cells and the cell's nucleus contains DNA. The induction of DNA damage...
Chromosomal translocations are a primary biological response to ionizing radiation (IR) exposure, an...
Homologous recombination (HR) and nonhomologous end-joining (NHEJ) are mechanistically distinct DNA ...
Homologous recombination is of major importance for the prevention of genomic instability during chr...
<div><p>Systems for the repair of DNA double-strand breaks (DSBs) are necessary to maintain genome i...
The aim of this thesis is to investigate the function of a number of genes involved in mammalian DN...
Regulation of the repair of DNA double-strand breaks by homologous recombination is extremely import...