Identifying central obesity as determinant of regression-to-normoglycaemia in patients with impaired fasting glucose

Conference Theme: The Obesity Wave: Understanding, Managing & Preventing Obesity and Metabolic SyndromeBackground: Fasting plasma glucose (FPG) is the most popular screening test for diabetes mellitus (DM) in Hong Kong primary care setting. Individuals with impaired fasting glucose (IFG) are commonly encountered. Objectives: To explore the determinants of regression-to-normoglycaemia among primary care patients with IFG based on non-invasive variables, and to establish a nomogram for the prediction of regression from IFG. Methods: This cohort study consisted of 1,197 primary care patients with confirmed IFG status. These subjects were invited to repeat a FPG test and 75-gram 2-hour oral glucose tolerance test (2h-OGTT) to determine the glycemic change within a period of 18 months. Normoglycaemia was defined as FPG<5.6 mmol/L and 2h-OGTT