Add to ORKGIn this paper we describe a combined in-vitro experimental and mathematical modelling approach to predict in-vivo drug-eluting stent kinetics. We coated stents with a mixture of sirolimus and a novel acrylic-based polymer in two different ratios. Our results indicate differential release kinetics between low and high drug dose formulations. Furthermore, mathematical model simulations of target receptor saturation suggest potential differences in efficacy
Drug-eluting stents are cardiovascular stents able to release a medical drug after implantation. The...
Drug-eluting stents implanted in blood vessels are subject to various dynamics of blood flow. In thi...
Drug-eluting stents have revolutionised the treatment of coronary artery disease. These small medica...
In this paper we describe a combined in-vitro experimental and mathematical modelling approach to pr...
In this paper we describe a combined in-vitro experimental and mathematical modelling approach to p...
In this study, we developed a predictive model of in vivo stent based drug release and distribution ...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Although drug-eluting stents (DES) are now widely used for the treatment of coronary heart disease, ...
With the aim of optimizing Drug Eluting Stents (DES), particular attention has been laid on computat...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
A computational model of the transport of drugs eluted from a drug-eluting stent (DES) in the arteri...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
Drug-eluting stents are cardiovascular stents able to release a medical drug after implantation. The...
Drug-eluting stents implanted in blood vessels are subject to various dynamics of blood flow. In thi...
Drug-eluting stents have revolutionised the treatment of coronary artery disease. These small medica...
In this paper we describe a combined in-vitro experimental and mathematical modelling approach to pr...
In this paper we describe a combined in-vitro experimental and mathematical modelling approach to p...
In this study, we developed a predictive model of in vivo stent based drug release and distribution ...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
A mathematical model of a drug-eluting stent is proposed. The model considers a polymer region, cont...
Although drug-eluting stents (DES) are now widely used for the treatment of coronary heart disease, ...
With the aim of optimizing Drug Eluting Stents (DES), particular attention has been laid on computat...
Drug-eluting stents have significantly improved the treatment of coronary artery disease. They offer...
A computational model of the transport of drugs eluted from a drug-eluting stent (DES) in the arteri...
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous b...
Drug-eluting stents are cardiovascular stents able to release a medical drug after implantation. The...
Drug-eluting stents implanted in blood vessels are subject to various dynamics of blood flow. In thi...
Drug-eluting stents have revolutionised the treatment of coronary artery disease. These small medica...