Correlation of dental caries, total proteins, total antioxidant capacity, immunoglobulin A and G in children at the age from 4-6 years

This study is aimed to : assess the level of total proteins in the saliva; to assess the level of the immunoglobulin’s IgA and IgG in the saliva; to assess the antioxidant capacity of the saliva; to analyze the correlation of the dental status and the level of activity of the dental caries in every examined parameter separately. Materials and methods: For the realization of our goals weincluded 74 preschool children (35 female and 39 male), picked randomly, at the age from 4-6 years, from the elementary schools in Shtip which were divided into two groups: experimental and control. Every examinee was clinically examined (dmft and intensity of dental caries) and laboratory investigations were carries out (total protein levels, antioxidant capacity, IgA and IgG in the saliva). Results: The results from our study that referred to the total amount of proteins in the saliva of children with primary teeth, from the control group, were significantly greater in correlation to the value of the same in children from the experimental group (p<0,01); we established a negative medium strong significant correlation (p<0,05) between the values of the total protein in the saliva of children with primary teeth and the presence of dental caries; the values of the total antioxidant capacity of the saliva in children with a primary dentition from the control group are significantly greater in correlation to the values of the same in the saliva of children from the experimental group (p<0,001); The examined correlation between the total antioxidant capacity of the saliva in children with primary dentition and the presence of dental caries, showed that there is a negative medium strong significant correlation (p<0,05; the levels of IgA and IgG in the saliva in children from the control group with primary dentition is significantly greater in correlation to the values of IgA and IgG in the saliva in children from the experimental group (p<0,001); the correlation between the values of the immunoglobulin A and G in the saliva of children with primary dentition and the presence of dental caries, showed that there is a negative medium strong significant correlation (p