Molecular mechanisms of capsaicin mediated cytotoxic activity

In the last few decades, capsaicin has exerted potent anti-cancer properties by enouncing anti-proliferative, apoptotic and anti-metastatic activity. To the best of our knowledge, the specific cell targets and successive mechanism of cytotoxic activity of capsaicin in different type of malignant cells, still remains unclear and contradictory. Therefore, this mini review, explains some of the most significant chemopreventive mechanisms of the action of capsaicin at a cellular level, reported in the recent literature