Add to ORKGLow weight at birth associates with subsequent susceptibility to diabetes. Epigenetic modulation is among the mechanisms potentially mediating this association. We performed a genome-wide DNA methylation analysis in placentas from term infants born appropriate-for-gestational-age (AGA) or small-for-gestational-age (SGA), to identify new genes related to fetal growth and neonatal body composition. Candidate genes were validated by bisulfite pyrosequencing (30 AGA, 21 SGA) and also analyzed in cord blood. Gene expression analyses were performed by RT-PCR. Neonatal body composition was assessed by dual X-ray absorptiometry at age 2 weeks. The ATG2B, NKX6.1 and SLC13A5 genes (respectively related to autophagy, beta-cell development and function...
Gestational diabetes and maternal obesity are associated with impaired maternal glycaemic control an...
Emerging evidence indicates that maternal medical risk during pregnancy, such as gestational diabete...
Background: Both higher and lower fetal growth are associated with cardio-metabolic health later in ...
Low weight at birth associates with subsequent susceptibility to diabetes. Epigenetic modulation is ...
Low weight at birth associates with subsequent susceptibility to diabetes. Epigenetic modulation is ...
Introduction Prenatal growth restraint followed by rapid postnatal weight gain increases lifelong di...
Background Birthweight marks an important milestone of health across the lifespan, including cardiom...
Inherent genetic programming and environmental factors affect fetal growth in utero. Epidemiologic d...
<p>Gestational diabetes mellitus (GDM) is associated with obesity in childhood. This suggests that c...
Although epigenetic regulation plays a critical role in embryonic development, few studies have exam...
BACKGROUND: Adiponectin critically contributes to metabolic homeostasis, especially by insulin-sensi...
We tested the hypothesis that gestational diabetes mellitus (GDM) alters the DNA methylation pattern...
Many epidemiological studies have linked low birthweight to an increased risk of non-communicable di...
Background: Insulin-like growth factors 1 and 2 (IGF1 and IGF2) and their binding proteins (IGFBPs)...
g.oxfordjournals.org/ D ow nloaded from 2 Exposure of a developing fetus to maternal gestational dia...
Gestational diabetes and maternal obesity are associated with impaired maternal glycaemic control an...
Emerging evidence indicates that maternal medical risk during pregnancy, such as gestational diabete...
Background: Both higher and lower fetal growth are associated with cardio-metabolic health later in ...
Low weight at birth associates with subsequent susceptibility to diabetes. Epigenetic modulation is ...
Low weight at birth associates with subsequent susceptibility to diabetes. Epigenetic modulation is ...
Introduction Prenatal growth restraint followed by rapid postnatal weight gain increases lifelong di...
Background Birthweight marks an important milestone of health across the lifespan, including cardiom...
Inherent genetic programming and environmental factors affect fetal growth in utero. Epidemiologic d...
<p>Gestational diabetes mellitus (GDM) is associated with obesity in childhood. This suggests that c...
Although epigenetic regulation plays a critical role in embryonic development, few studies have exam...
BACKGROUND: Adiponectin critically contributes to metabolic homeostasis, especially by insulin-sensi...
We tested the hypothesis that gestational diabetes mellitus (GDM) alters the DNA methylation pattern...
Many epidemiological studies have linked low birthweight to an increased risk of non-communicable di...
Background: Insulin-like growth factors 1 and 2 (IGF1 and IGF2) and their binding proteins (IGFBPs)...
g.oxfordjournals.org/ D ow nloaded from 2 Exposure of a developing fetus to maternal gestational dia...
Gestational diabetes and maternal obesity are associated with impaired maternal glycaemic control an...
Emerging evidence indicates that maternal medical risk during pregnancy, such as gestational diabete...
Background: Both higher and lower fetal growth are associated with cardio-metabolic health later in ...