Cardiovascular Abnormalities in Egyptian Children with Mucopolysaccharidoses
- Selim, Laila
- Abdelhamid, Nehal
- Salama, Emad
- Elbadawy, Amera
- Gamaleldin, Iman
- Ibrahim, Mohamed
- Selim, Abeer
DOIAbstract
The Mucopolysaccharidoses (MPS) are rare inherited metabolic disorders. They are characterized by the progressive systemic deposition of Glycosaminoglycans (GAGs). GAGs accumulate in the myocardium and the cardiac valves. Enzyme Replacement Therapy (ERT) is available for MPS I, II, and VI. However, ERT does not appear to improve cardiac valve disease in patients with valve disease present at the start of ERT.status: publishe
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