Aberrant collagen composition of the trabecular meshwork results in reduced aqueous humor drainage and elevated IOP in MMP-9 null mice
- De Groef, Lies
- Andries, Lien
- Siwakoti, Anuja
- Geeraerts, Emiel
- Bollaerts, Ilse
- Noterdaeme, Lut
- Etienne, Isabelle
- Papageorgiou, Anna-Pia
- Stalmans, Ingeborg
- Billen, Johan
- West-Mays, Judith A.
- Moons, Lieve
Publication date
November 2016
DOI Publisher
Association for Research in Vision and Ophthalmology ISSN
1552-5783 Journal
issn:1552-5783 Citation count (estimate)
4Abstract
Homeostatic turnover of the trabecular meshwork extracellular matrix (ECM) is essential to regulate aqueous humor outflow and to maintain intraocular pressure homeostasis. In this study, we evaluated aqueous humor turnover, intraocular pressure, and trabecular meshwork organization in MMP-9 null mice.status: publishe
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