Add to ORKGA series of cinnamaldehydes was synthesized for the study of inhibitory activity against cyclin dependent kinases (CDKs). A couple of compounds selectively inhibited cyclin D1-CDK4 with an IC50 value of 7-18 μM.ope
Novel purine-2,6-diamine derivatives were designed and synthesized as cyclin-dependent kinase (CDK) ...
International audienceWe here report the synthesis and biological evaluation of new 3-[(2-indolyl)]-...
Cyclin-Dependent Kinases (CDKs) are a family of protein kinases that control progression through the...
A series of cinnamaldehydes was synthesized for the study of inhibitory activity against cyclin depe...
Synthesis of novel inhibitors of CDK 4 / Cyclin D1 based on the natural marine sponge pigment fascap...
prime target for the treatment of cancer because most hu-man cancers are characterized by overexpres...
Novel purine-2, 6-diamine derivatives were designed and synthesized as cyclin-dependent kinase (CDK)...
A series of 2-hydroxycinnamaldehyde derivatives was synthesized for examing a structure-activity rel...
<p>Values are presented as means±SD from 3 independent experiments.</p>a<p>GI<sub>50</sub>∶50% growt...
This thesis describes an investigation into the design and synthesis of novel inhibitors of the cell...
Because of frequent alterations of cell cycle regulatory genes (including cyclins, cyclin-dependent ...
This thesis describes an investigation into the design and synthesis of novel inhibitors of the cell...
We accomplished divergent synthesis of potent kinase inhibitor BAY 61-3606 (1) and 27 derivatives vi...
Cyclin-dependent kinases (Cdk) and their associated pathways represent some of the most attractive t...
Available from British Library Document Supply Centre-DSC:DXN031901 / BLDSC - British Library Docume...
Novel purine-2,6-diamine derivatives were designed and synthesized as cyclin-dependent kinase (CDK) ...
International audienceWe here report the synthesis and biological evaluation of new 3-[(2-indolyl)]-...
Cyclin-Dependent Kinases (CDKs) are a family of protein kinases that control progression through the...
A series of cinnamaldehydes was synthesized for the study of inhibitory activity against cyclin depe...
Synthesis of novel inhibitors of CDK 4 / Cyclin D1 based on the natural marine sponge pigment fascap...
prime target for the treatment of cancer because most hu-man cancers are characterized by overexpres...
Novel purine-2, 6-diamine derivatives were designed and synthesized as cyclin-dependent kinase (CDK)...
A series of 2-hydroxycinnamaldehyde derivatives was synthesized for examing a structure-activity rel...
<p>Values are presented as means±SD from 3 independent experiments.</p>a<p>GI<sub>50</sub>∶50% growt...
This thesis describes an investigation into the design and synthesis of novel inhibitors of the cell...
Because of frequent alterations of cell cycle regulatory genes (including cyclins, cyclin-dependent ...
This thesis describes an investigation into the design and synthesis of novel inhibitors of the cell...
We accomplished divergent synthesis of potent kinase inhibitor BAY 61-3606 (1) and 27 derivatives vi...
Cyclin-dependent kinases (Cdk) and their associated pathways represent some of the most attractive t...
Available from British Library Document Supply Centre-DSC:DXN031901 / BLDSC - British Library Docume...
Novel purine-2,6-diamine derivatives were designed and synthesized as cyclin-dependent kinase (CDK) ...
International audienceWe here report the synthesis and biological evaluation of new 3-[(2-indolyl)]-...
Cyclin-Dependent Kinases (CDKs) are a family of protein kinases that control progression through the...