Changes in the intracellular free calcium concentration ([Ca2+]i) in neurons regulates many and varied aspects of neuronal function over time scales from microseconds to days. The mystery is how a single signalling ion can lead to such diverse and specific changes in cell function. This is partly due to aspects of the Ca2+ signal itself including its magnitude, duration, localisation and its persistent or oscillatory nature. The transduction of the Ca2+ signal requires Ca2+ binding to various Ca2+ sensor proteins. The different properties of these sensors are important for differential signal processing and determine the physiological specificity of Ca2+ signalling pathways. A major factor underlying the specific roles of particular Ca2+ s...
In the course of evolution, Ca2+ has emerged as the most versatile intracellular messenger. Its conc...
Calcium (Ca2+) is an almost universal intracellular messenger, controlling a diverse range of cellul...
A critical role of Ca2+ in neuronal signaling is to couple electrical excitation to the activation o...
AbstractChanges in the intracellular free calcium concentration ([Ca2+]i) in neurons regulate many a...
AbstractChanges in intracellular free Ca2+ concentration ([Ca2+]i) affect many different aspects of ...
Abstract Calcium signalling plays a crucial role in the control of neuronal function and plasticity....
The cytoplasmic free Ca2+ concentration ([Ca2+]i) is a key determinant of neuronal information trans...
AbstractTransient rises in the cytoplasmic concentration of calcium ions serve as second messenger s...
Ca2+ signaling in neurons is characterized by highly restricted and dynamic gradients called Ca2+ wa...
Calcium (Ca2+) is a fundamental intracellular signalling molecule in neurons. Therefore, significant...
Intracellular Ca2+ controls such diverse processes as growth, cell division, contraction, secretion,...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
Neuronal calcium acts as a charge carrier during information processing and as a ubiquitous intracel...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
Calcium fluxes through the neuronal membrane are strictly limited in time due to biophysical propert...
In the course of evolution, Ca2+ has emerged as the most versatile intracellular messenger. Its conc...
Calcium (Ca2+) is an almost universal intracellular messenger, controlling a diverse range of cellul...
A critical role of Ca2+ in neuronal signaling is to couple electrical excitation to the activation o...
AbstractChanges in the intracellular free calcium concentration ([Ca2+]i) in neurons regulate many a...
AbstractChanges in intracellular free Ca2+ concentration ([Ca2+]i) affect many different aspects of ...
Abstract Calcium signalling plays a crucial role in the control of neuronal function and plasticity....
The cytoplasmic free Ca2+ concentration ([Ca2+]i) is a key determinant of neuronal information trans...
AbstractTransient rises in the cytoplasmic concentration of calcium ions serve as second messenger s...
Ca2+ signaling in neurons is characterized by highly restricted and dynamic gradients called Ca2+ wa...
Calcium (Ca2+) is a fundamental intracellular signalling molecule in neurons. Therefore, significant...
Intracellular Ca2+ controls such diverse processes as growth, cell division, contraction, secretion,...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
Neuronal calcium acts as a charge carrier during information processing and as a ubiquitous intracel...
A calcium signal is a sudden increase in the concentration of calcium ions (Ca2+) in the cytosol. Su...
Calcium fluxes through the neuronal membrane are strictly limited in time due to biophysical propert...
In the course of evolution, Ca2+ has emerged as the most versatile intracellular messenger. Its conc...
Calcium (Ca2+) is an almost universal intracellular messenger, controlling a diverse range of cellul...
A critical role of Ca2+ in neuronal signaling is to couple electrical excitation to the activation o...