The influence of early reinfusion of autologous shed mediastinal blood on the postoperative course after cardiac surgery

Perioperative bleeding, anaemia, allogeneic blood trans¬fusions and transfusion associated complications – all these factors are closely interrelated and contribute to the increase in the cost of treat¬ment, thereby remain the relevant problem in cardiac surgery. The appropriate alternative to allogeneic blood transfusion is the use of autologous blood. The aim of the study: to evaluate the influence of early reinfusion of collected autologous shed mediastinal blood on a patient’s postoperative course after cardiac surgery. The objectives of the study: 1.To evaluate the workflow features of early postoperative course of patients who underwent reinfusion of shed mediastinal blood after heart surgery. To determine the effects of collected and reinfused autologous shed blood: on the intensity of postoperative bleeding; on the changes in haemoglobin concentration, haematocrit value, number of blood formed elements; on the changes in indices of blood coagulation and fibrinolysis; on the changes in blood inflammatory markers; on the intensity of haemolysis and renal function; on mechanical lung ventilation time and postoperative requirement for catecholamines. 2. To evaluate the effect of reinfusion of autologous shed blood on the postoperative requirement for donor blood components. 3. To evaluate the effect of reinfusion of autologous shed blood on the risk of postoperative complications and length of hospital stay. 4. To determine prognostic value of early reinfusion of collected shed mediastinal blood on the patients postoperative course