Evaluation of the effect of long-term training on cardiorespiratory function, chronic fatigue and quality of life of patients with stable chronic heart failure

Evaluation of the effect of long-term training on cardiorespiratory function, chronic fatigue and quality of life of patients with stable chronic heart failure Objectives of the study: 1. To evaluate the effect of additional complex rehabilitative measures to clinical state, cardiorespiratory function, left ventricle remodeling, quality of life and fatigue in patients with severe and particularly severe heart failure. 2. To assess the relationship between parameters of cardiorespiratory functions measured by various methods (two-dimensional echocardiography, spiroergometry, 6-minute walk test) in patients with moderate and severe heart failure after long-term physical training. 3. To evaluate the safety of long-term physical training for patients with moderate and severe heart failure. After 6 months aerobic staged physical training of patients with moderate and severe HF there was statistically significant changes in clinical condition: increase of NYHA HF functional class, increase of quality of life and decrease of fatigue; respiratory function: respiratory volume increased by 2.4±0.8 l/min and oxygen consumption by 2 ml/kg/min; physical capacity: physical workload increased by 18.0±3.6 W and exercise duration increased by 2.4±3.3 minutes in trained patients. Long-term physical training is safe for patients with moderate and severe HF: during study period there were significantly fewer deaths and cardiovascular hospitalizations, in comparison with the patients who were provided with medical treatment