Evaluation of diagnostic criteria for metabolic syndrome to identify insulin resistance

The aim of study was to evaluate the possibilities of different diagnostic criteria for metabolic syndrome in identifying subjects with insulin resistance and to assess the prevalence of metabolic syndrome according to gender in one Lithuanian district. Materials and methods. A randomly selected sample of 1,115 subjects aged 45–96 years (562 men and 553 women) was formed from general population of Raseiniai district. Insulin resistance was estimated using the homeostasis model assessment. Metabolic syndrome was determined according to the definitions of the World Health Organization, National Cholesterol Education Program Adults Treatment Panel III, and International Diabetes Federation. Results. Using the World Health Organization criteria, metabolic syndrome was observed in 384 (34.4%) subjects (no difference between genders); according to the National Cholesterol Education Program – in 336 (30.1%) patients (in 107 men (19.0%) and 229 women (41.4%), p<0.001); using International Diabetes Federation criteria – in 474 (42.5%) (175 men (31.1%) and 299 women (54.1%), p<0.001). Overall, 314 (28.5%) subjects were insulin resistant (no difference between genders). The highest prevalence of insulin resistance was determined in subjects with metabolic syndrome diagnosed according to the World Health Organization criteria – 70.3% (n=267), p