Mast cell count in canine mammary gland tumors and relation with angioneogenesis

Mammary gland tumors are one of the most common cannine tumors. The main factor affecting neoplasm proliferation is angioneogenesis. The more vasculiarised the toumor tissue is the faster it grows and the grater chance of metastasis to other organs. The purpouse of the study was to find the correlation between angioneogenesis and mast cell cout in cannine mammary gland tumors. Mammary gland tumour samples were taken during surgery at Dr. L. Kriaučeliūnas small animal clinic of Lithuanian University of Health Sciences and in small animal clinic in Klaipeda. From the taken samples histological specimens were made at the Centre of Pathology of Lithuanian University of Health Sciences. Immunohistochemical reactions using immunohistochemical marker CD31 were made at Department of Histology and Embryology of Lithuanian University of Health Sciences. In the prepared samples mast cells and new capillaries were counted. Correlation coefficient was calculated (0,7), witch shows a strong affinity between mast cell count and count newlly formed blood vessles in canine mammary gland tumors. Anamnesis vitae was colected and reacerch about:brees, sex, and age presisposition was made. The probobility of the differences between two supplied data sets was calculated. The differences were statisticly significent if p