Fluktuasi Kadar Tsh dan Free T4 Selama Suplementasi Spirulina sebagai Sumber Iodium Alami pada Wanita Usia Subur di Daerah Endemik Gaki

Spirulina is seawater microalgae that have potential as natural source of iodine and contain of 94.5 ppm iodine. The purpose of this study was to determine the effect of spirulina consumption on TSH and fT4 level at women of childbearing age in IDD (Iodine Deficiency Disorder) endemicarea, who at risk of hypothyroidism. This is a Randomized Control Trial (RCT), double-blind research. Subjects were women of childbearing age (18-40 years), with TSH levels 3 to 6.2 μIU /L, divided into 2 groups. The control group was given placebo and the treatment group were given spirulina, 1 g/day, for 3 months. Spirulina and placebo were capsulated in similar capsul. TSH and FT4 levels were analyzed by ELISA method from blood serum samples. Two cc of blood were taken from subjects arm vein. The results showed that spirulina supplementation did not affect TSH levels (P > 0.05), but increasing thyroid hormone levels (fT4) higher than the control group (P 0,05), namun dapat meningkatkan kadar hormon tiroid fT4 lebih tinggi dibandingkan kelompok kontrol (P < 0,05). Spirulina bisa menjadi alternatif sumber iodium selain garam untuk meningkatkan fungsitiroid.Kata kunci : iodium, fT4, spirulina, TS