Cytotoxicity and antibacterial activity of polar extracts obtained from saffron (Crocus sativus L.) Floral bio-residues

Saffron (Crocus sativus L.) flower comprises six purple tepals, three yellow stamens and a white filiform style ending in a stigma with three threads, which represents less than 10% (w/w) of the flower weight. However, the stigma is the dominant reason to farm/harvest saffron, since it represents the most valued spice (after being dried). Interesting large amounts of floral bio-residues are produced and wasted from this action, considering that a single kg of saffron spice generates ~63 kg of floral bioresidues. This scenario creates opportunities for the extended use of this discarded material, particularly owing to its important bioactive compounds and related health promoting properties, such as antioxidant, antityrosinase, antidepressant, antifungal, antinociceptive, anti-inflammatory and arterial pressure reduction.N/