BACKGROUND: The incidence of chronic myeloid leukemia (CML) increases with age, but it is unclear how the characteristics of the disease vary with age. In children, where CML is very rare, it presents with more aggressive features, including huge splenomegaly, higher cell count and higher blast cell percentage. PATIENTS AND METHODS: To investigate if after childhood the disease maintains or loses these characteristics of aggressiveness, we analyzed 2784 adult patients, at least 18 years old, registered by GIMEMA CML WP over a 40-year period. RESULTS: Young adults (YAs: 18-29 years old) significantly differed from adults (30-59 years old) and elderly patients (at least 60 years old) particularly for the frequency of splenomegaly (71%, 6...
An observational prospective study was conducted by the CML Italian network to analyze the role of b...
Chronic myelomonocytic leukemia (CMML) is a disease of the elderly, and by far the most frequent ove...
About 40% of all patients with chronic myeloid leukemia are currently old or very old. They are effe...
Background: The incidence of chronic myeloid leukemia (CML) increases with age, but it is unclear ho...
Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rig...
Abstract BACKGROUND: The incidence of chronic myeloid leukemia (CML) increases with age, but it ...
The incidence of chronic myeloid leukemia (CML) increases with age, but it is unclear how the charac...
In patients with chronic myelomonocytic leukemia (CMML), age>65 years is an adverse prognostic facto...
There are established guidelines for treatment and monitoring of chronic myeloid leukemia (CML) but ...
To assess the effect of age on response and compliance to treatment in patients with chronic myeloid...
leukemia (CML) patients (22% in a population-based registry study performed in Europe) (Hoffman V e...
Objectives To examine contemporary survival patterns in the general population of patients diagnosed...
An observational prospective study was conducted by the CML Italian network to analyze the role of b...
Chronic myelomonocytic leukemia (CMML) is a disease of the elderly, and by far the most frequent ove...
About 40% of all patients with chronic myeloid leukemia are currently old or very old. They are effe...
Background: The incidence of chronic myeloid leukemia (CML) increases with age, but it is unclear ho...
Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rig...
Abstract BACKGROUND: The incidence of chronic myeloid leukemia (CML) increases with age, but it ...
The incidence of chronic myeloid leukemia (CML) increases with age, but it is unclear how the charac...
In patients with chronic myelomonocytic leukemia (CMML), age>65 years is an adverse prognostic facto...
There are established guidelines for treatment and monitoring of chronic myeloid leukemia (CML) but ...
To assess the effect of age on response and compliance to treatment in patients with chronic myeloid...
leukemia (CML) patients (22% in a population-based registry study performed in Europe) (Hoffman V e...
Objectives To examine contemporary survival patterns in the general population of patients diagnosed...
An observational prospective study was conducted by the CML Italian network to analyze the role of b...
Chronic myelomonocytic leukemia (CMML) is a disease of the elderly, and by far the most frequent ove...
About 40% of all patients with chronic myeloid leukemia are currently old or very old. They are effe...