Abstract Women with breast cancer (BC) and antithyroid peroxidase (TPO) autoantibodies (TPOAb) have a better prognosis than women lacking TPOAb. Sera from women with TPOAb displayed immunoreactivity to BC tissue by immunofluorescence that was not apparent in women without TPOAb. We hypothesize a BC/thyroid shared antigen that provides a target for humoral or cell-mediated immune activity; candidates include the sodium/iodide symporter (expressed in thyroid and BC), cross-reacting epitopes in TPO and lactoperoxidase (LPO) or TPO itself. As the association is with TPOAb, we investigated TPO expression in BC, breast peritumoral tissue (PT), other tissues (tumoral and not) and thyroid as positive control. Transcripts for known and novel TPO ...
Many scientific researches have focused attention to the possible associations between breast cancer...
<p><b>The expression of lactoperoxidase (LPO) in breast tissues (A and B) and cell lines (C and D) d...
Thyroid peroxidase (TPO) is an enzyme that participates in thyroid hormone biosynthesis. TPO is also...
Women with breast cancer (BC) and antithyroid peroxidase (TPO) autoantibodies (TPOAb) have a better ...
Thyroid peroxidase (TPO) is essential for physiological function of the thyroid gland. The high prev...
The association between breast cancer and benign thyroid disorders, in particular thyroid autoimmuni...
Purpose Anti-thyroid peroxidase (TPO) autoantibodies (TPOAb) seem to be protective for patients with...
<p>Representative immunostaining results obtained with a panel of monoclonal antibodies (mAbs), (A) ...
Abstract An association between thyroid autoimmunity and breast cancer (BC) has been consistently...
There is disagreement concerning the expression of thyroid peroxidase (TPO) in thyroid cancer, some ...
Thyroid peroxidase (TPO) is an enzyme and autoantigen expressed in thyroid and breast tissues. Thyro...
<div><p>Thyroid peroxidase (TPO) is an enzyme and autoantigen expressed in thyroid and breast tissue...
Thyroid hormones influence both normal breast cell differentiation and breast cancer cell proliferat...
<p><b>Representative TPO immunostaining results obtained with a panel of monoclonal antibodies (mAbs...
<p><b>The biochemical properties of TPO protein expressed in breast tissues (A and B) and breast-der...
Many scientific researches have focused attention to the possible associations between breast cancer...
<p><b>The expression of lactoperoxidase (LPO) in breast tissues (A and B) and cell lines (C and D) d...
Thyroid peroxidase (TPO) is an enzyme that participates in thyroid hormone biosynthesis. TPO is also...
Women with breast cancer (BC) and antithyroid peroxidase (TPO) autoantibodies (TPOAb) have a better ...
Thyroid peroxidase (TPO) is essential for physiological function of the thyroid gland. The high prev...
The association between breast cancer and benign thyroid disorders, in particular thyroid autoimmuni...
Purpose Anti-thyroid peroxidase (TPO) autoantibodies (TPOAb) seem to be protective for patients with...
<p>Representative immunostaining results obtained with a panel of monoclonal antibodies (mAbs), (A) ...
Abstract An association between thyroid autoimmunity and breast cancer (BC) has been consistently...
There is disagreement concerning the expression of thyroid peroxidase (TPO) in thyroid cancer, some ...
Thyroid peroxidase (TPO) is an enzyme and autoantigen expressed in thyroid and breast tissues. Thyro...
<div><p>Thyroid peroxidase (TPO) is an enzyme and autoantigen expressed in thyroid and breast tissue...
Thyroid hormones influence both normal breast cell differentiation and breast cancer cell proliferat...
<p><b>Representative TPO immunostaining results obtained with a panel of monoclonal antibodies (mAbs...
<p><b>The biochemical properties of TPO protein expressed in breast tissues (A and B) and breast-der...
Many scientific researches have focused attention to the possible associations between breast cancer...
<p><b>The expression of lactoperoxidase (LPO) in breast tissues (A and B) and cell lines (C and D) d...
Thyroid peroxidase (TPO) is an enzyme that participates in thyroid hormone biosynthesis. TPO is also...