Encefaliti ad eziologia sconosciuta nel cane e gatto

A case of canine granulomatous meningoencephalitis (CGME) and a case of feline polioencephalomyelitis or staggering disease are described and the encephalitides of unknown etiology reported in domestic carnivores are briefly reviewed. The CGME was observed in a Yorkshire terrier, male, 1.5 year-old and was characterized by perivascular accumulation of large mononuclear cells, lymphocytes and plasmacells. In the feline non suppurative polioencephalomyelitis, a few perivascular cuffs of lymphocytes and plasmacells, focal microgliosis and neuronophagia, confined in the brain stem and in the spinal cord, were observed. Clinical and immunohistochemical studies, carried out to identify the presence of the most common viral infections gave negative results