Add to ORKGBromination of cepham I with 2,6-lutidine Br complex gave II (R = Br), which was treated with DMF/H2O to give II (R = OCHO)
Two types of systems are discussed. The first one is derived from lutidine, which either is condense...
The rates of thiolysis of cephalosporins were investigated by high-performance liquid chromatography...
The synthesis of four candidate stereoisomers of cephalosporolide H is described, made possible by a...
2-cephem allylic bromides are important, versatile intermediates for the derivatization of C-3’ posi...
Spiro compounds provide attractive targets in drug discovery due to their inherent three-dimensional...
Reaction of a 2β-bromomethyl penam with triphenyltin hydride gave, via ring expansion of the derived...
Hydrolysis of beta-lactam antibiotics by beta-lactamases (e. g., metallo-beta-lactamase, m beta l) i...
This thesis deals with selective complexation of the Ø-lactam antibiotics Cephalexin, Cephradine, Ce...
3-Bromomethyl-3 cephems are solvolysed by alcohols, similarly to the Δ2 isomers. The yields are fai...
Cephalosporolide B (Ces-B) was efficiently synthesized and exploited for the first time as a versati...
New derivatives of 7-aminocephalosporanic acid 1–8 were synthesized by acylation of the 7-amino grou...
The p-nitrobenzoates I were stereospecifically transformed with AgOAc-AcOH into the penam derivs. II...
Pieper M, Schleich H, Gröger H. General Synthesis of Industrial Cephalosporin-Based Antibiotics Thro...
Cephalotaxiane and a variety of (alpha)-hydroxysuccinate esters of cephalotaxine known as the harrin...
The effect of replacing the -lactam carbonyl oxygen in cephalosporins by sulfur on their reactivity ...
Two types of systems are discussed. The first one is derived from lutidine, which either is condense...
The rates of thiolysis of cephalosporins were investigated by high-performance liquid chromatography...
The synthesis of four candidate stereoisomers of cephalosporolide H is described, made possible by a...
2-cephem allylic bromides are important, versatile intermediates for the derivatization of C-3’ posi...
Spiro compounds provide attractive targets in drug discovery due to their inherent three-dimensional...
Reaction of a 2β-bromomethyl penam with triphenyltin hydride gave, via ring expansion of the derived...
Hydrolysis of beta-lactam antibiotics by beta-lactamases (e. g., metallo-beta-lactamase, m beta l) i...
This thesis deals with selective complexation of the Ø-lactam antibiotics Cephalexin, Cephradine, Ce...
3-Bromomethyl-3 cephems are solvolysed by alcohols, similarly to the Δ2 isomers. The yields are fai...
Cephalosporolide B (Ces-B) was efficiently synthesized and exploited for the first time as a versati...
New derivatives of 7-aminocephalosporanic acid 1–8 were synthesized by acylation of the 7-amino grou...
The p-nitrobenzoates I were stereospecifically transformed with AgOAc-AcOH into the penam derivs. II...
Pieper M, Schleich H, Gröger H. General Synthesis of Industrial Cephalosporin-Based Antibiotics Thro...
Cephalotaxiane and a variety of (alpha)-hydroxysuccinate esters of cephalotaxine known as the harrin...
The effect of replacing the -lactam carbonyl oxygen in cephalosporins by sulfur on their reactivity ...
Two types of systems are discussed. The first one is derived from lutidine, which either is condense...
The rates of thiolysis of cephalosporins were investigated by high-performance liquid chromatography...
The synthesis of four candidate stereoisomers of cephalosporolide H is described, made possible by a...