This paper demonstrates a way of solving industrial aerodynamic shape optimization problems using the RBF4AERO platform, developed in the framework of the EU–funded RBF4AERO project. The platform combines optimization algorithms (stochastic and gradient– based ones), a mesh morphing tool based on Radial Basis Functions (RBFs) and various evaluation tools (CFD, CSD, etc). In this paper, the Evolutionary Algorithms (EAs) based tool assisted by metamodels trained on a sampling performed during the Design of Experiment phase is used along with a CFD evaluation tool. The use of Response Surface Models (RSM) significantly reduces the number of CFD runs required to reach the optimal solution(s), while the use of RBF–based mesh morphing avoids re–m...