A Four-Year Longitudinal Study on Restless Legs Syndrome in Parkinson Disease
- Moccia, Marcello
- Santangelo, Gabriella
- Spina, Emanuele
- Allocca, Roberto
- Longo, Katia
- Palladino, Raffaele
- Assante, Roberta
- Pappatà, Sabina
- Vitale, Carmine
- ERRO, ROBERTO
- PICILLO, MARINA
- AMBONI, MARIANNA
- PELLECCHIA, MARIA TERESA
- BARONE, Paolo
DOIAbstract
Restless legs syndrome (RLS) has a prevalence of 0% to 52% in Parkinson disease (PD). However, it is still debated whether RLS in PD is a premotor feature, a motor complication, or an association by chance. The present study aims to evaluate RLS prevalence in de novo PD subjects, and incidence during 4-year follow-up, together with laboratory, clinical, and neuroradiological correlates
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