International audienceWe present a tentative detection of the large-scale structure of Ly alpha emission in the Universe at redshifts z = 2-3.5 by measuring the cross-correlation of Ly alpha surface brightness with quasars in Sloan Digital Sky Survey/Baryon Oscillation Spectroscopic Survey. We use amillion spectra targeting luminous red galaxies at z \textless 0.8, after subtracting a best-fitting model galaxy spectrum from each one, as an estimate of the high-redshift Ly alpha surface brightness. The quasar-Ly alpha emission cross-correlation is detected on scales 1 similar to 15 h(-1) Mpc, with shape consistent with a Lambda CDM model with Omega(m) = 0.30(-0.07)(+0.10). The predicted amplitude of this cross-correlation is proportional to ...