The bactericidal effects of amoxycillin and ticarcillin in the presence of clavulanic acid against /Mactamase-producing bacteria were investigated in m-vitro kinetic models. Amoxycillin/clavulanic acid was rapidly bactericidal as a simulated intravenous 1 2 g bolus dose, against a strain of Klebsiella pneumoniae highly resistant to amoxycillin. Similarly, ticarcillin/clavulanic acid at concentrations similar to those achieved with a 30 min IV infusion of ticarcillin/clavulanic acid (5 0 g/200 mg) produced bactericidal effects against a ticarcillin-resistant strain of Pseudomonas aeruginosa. Addition of gentamicin to the system resulted in a further enhancement of activity
In an open, non-comparative study 40 patients with severe, often life-threatening infections, were t...
SummaryObjectives:A new, pharmacokinetically enhanced, oral formulation of amoxicillin/clavulanic ac...
The experimental and clinical values of amoxycillin/clavulanate in severe Staphylococcus aureus infe...
Amoxycillin/clavulanic acid and clavulanic acid have been previously reported to demonstrate bacteri...
ObjectiveThe purpose of this study was to investigate and characterize in vitro the post-β-lactamase...
The activity of amoxycillin/clavulanic acid (Augmentin) and ticarcillin/clavulanic acid (Timentin) w...
SUMMARY The pharmacokinetics and clinical efficacy of amoxycillin combined with clavulanic acid in t...
AbstractObjective To study the pharmacodynamics of amoxicillin/clavulanic acid against different str...
This study investigated the effects of c1avulanate-potentiated amoxyciJIin in the management of mode...
Clavulanic acid (CLA) exhibits low MICs against some Acinetobacter baumannii strains. The present st...
Clavulanate is a broad-spectrum β-lactamase inhibitor, with activity against many of the chromosomal...
The activity of amoxycillin/clavulanate (Augmentin) and ticarcillin/ clavulanate (Timentin) was test...
Combination of amoxicillin/clavulanate firstly occurred on a pharmacological market in 1977 and it i...
The activity of amoxycillin/clavulanate(Augmentin(R)) and ticarcillin/clavulanate (Timentin(R)) was ...
A clinical trial with Timentin (ticarcillin plus clavulanic acid) was undertaken in patients with ho...
In an open, non-comparative study 40 patients with severe, often life-threatening infections, were t...
SummaryObjectives:A new, pharmacokinetically enhanced, oral formulation of amoxicillin/clavulanic ac...
The experimental and clinical values of amoxycillin/clavulanate in severe Staphylococcus aureus infe...
Amoxycillin/clavulanic acid and clavulanic acid have been previously reported to demonstrate bacteri...
ObjectiveThe purpose of this study was to investigate and characterize in vitro the post-β-lactamase...
The activity of amoxycillin/clavulanic acid (Augmentin) and ticarcillin/clavulanic acid (Timentin) w...
SUMMARY The pharmacokinetics and clinical efficacy of amoxycillin combined with clavulanic acid in t...
AbstractObjective To study the pharmacodynamics of amoxicillin/clavulanic acid against different str...
This study investigated the effects of c1avulanate-potentiated amoxyciJIin in the management of mode...
Clavulanic acid (CLA) exhibits low MICs against some Acinetobacter baumannii strains. The present st...
Clavulanate is a broad-spectrum β-lactamase inhibitor, with activity against many of the chromosomal...
The activity of amoxycillin/clavulanate (Augmentin) and ticarcillin/ clavulanate (Timentin) was test...
Combination of amoxicillin/clavulanate firstly occurred on a pharmacological market in 1977 and it i...
The activity of amoxycillin/clavulanate(Augmentin(R)) and ticarcillin/clavulanate (Timentin(R)) was ...
A clinical trial with Timentin (ticarcillin plus clavulanic acid) was undertaken in patients with ho...
In an open, non-comparative study 40 patients with severe, often life-threatening infections, were t...
SummaryObjectives:A new, pharmacokinetically enhanced, oral formulation of amoxicillin/clavulanic ac...
The experimental and clinical values of amoxycillin/clavulanate in severe Staphylococcus aureus infe...