Longitudinal Associations Between Changes in Physical Activity and Onset of Type 2 Diabetes in Older BritishMen The influence of adiposity

OBJECTIVEdTo determine how much physical activity (PA) is needed to protect against diabetes onset in older adults, whether protection is greater among overweight individuals, and whether taking up moderate activity in later life is beneficial. RESEARCH DESIGN AND METHODSdMen (4,252) from a U.K. population-based cohort self-reported usual PA (regular walking and cycling, recreational activity, and sport) in 1996 and in 1998–2000, alongside other health behaviors and medical history. Fasting blood lipids were measured. Median follow-up was 7.1 years, during which 135 cases of type 2 diabetes (validated self-report) occurred. RESULTSdAmong 3,012 men free from cardiovascular disease and diabetes in 1998–2000