expression, testis Domestic pigs have three CYP19 genes encoding functional paralogues of the enzyme aromatase cytochrome P450 (P450arom) that are expressed in the gonads, placenta and pre-implantation blastocyst. All catalyze estrogen synthesis, but the "gonadal " type enzyme is unique in also synthesizing a non-aromatizable, biopotent testosterone metabolite, 1OH-testosterone (1OH-T). P450arom is expressed in the vertebrate brain, is higher in males than females, but has not been investigated in pigs. Therefore, these studies defined which of the porcine CYP19 genes was expressed, and at what level, in adult male and female hypothalamus. Regional expression was examined in mature boars, and regulation of P450arom expression in n...
Despite the fact that pigs are increasingly used in pharmacological and toxicological studies, knowl...
Porcine tissue gene expression is highly similar to the expression of homologous genes in humans. Ba...
Cytochrome P450 (CYP450) is the major family of enzymes involved in the metabolism of several xenobi...
Domestic pigs have three CYP19 genes encoding functional paralogues of the enzyme aromatase cytochro...
Cytochrome P450 aromatase is the key enzyme in estrogen biosynthesis, encoded by CYP19 gene. Impairm...
Proper, tissue-specific regulation of CYP19, the gene encoding aromatase, the key enzyme of estrogen...
In Meishan and Landrace pigs, sex-differences in the constitutive expression of hepatic cytochrome P...
Abstract Background Boar taint is an unpleasant odor and flavor of the meat and occurs in a high pro...
Porker immunocastration against gonadoliberin (GnRH) secretion has been utilized since 2009; however...
Sexual differentiation and early embryonic/fetal gonad development is a tightly regulated process co...
In mammals, testis development is initiated in the embryo as a response to the expression of the sex...
Production of steroid hormones is complex and dependent upon steroidogenic enzymes, cofactors, recep...
Mammalian testis contains D-aspartic acid (D-Asp), which enhances testosterone production. D-Asp, on...
Intersexuality has been reported in pigs and investigations are in progress to identify and physical...
<div><p>Boar taint is an offensive odour and/or taste from a proportion of non-castrated male pigs c...
Despite the fact that pigs are increasingly used in pharmacological and toxicological studies, knowl...
Porcine tissue gene expression is highly similar to the expression of homologous genes in humans. Ba...
Cytochrome P450 (CYP450) is the major family of enzymes involved in the metabolism of several xenobi...
Domestic pigs have three CYP19 genes encoding functional paralogues of the enzyme aromatase cytochro...
Cytochrome P450 aromatase is the key enzyme in estrogen biosynthesis, encoded by CYP19 gene. Impairm...
Proper, tissue-specific regulation of CYP19, the gene encoding aromatase, the key enzyme of estrogen...
In Meishan and Landrace pigs, sex-differences in the constitutive expression of hepatic cytochrome P...
Abstract Background Boar taint is an unpleasant odor and flavor of the meat and occurs in a high pro...
Porker immunocastration against gonadoliberin (GnRH) secretion has been utilized since 2009; however...
Sexual differentiation and early embryonic/fetal gonad development is a tightly regulated process co...
In mammals, testis development is initiated in the embryo as a response to the expression of the sex...
Production of steroid hormones is complex and dependent upon steroidogenic enzymes, cofactors, recep...
Mammalian testis contains D-aspartic acid (D-Asp), which enhances testosterone production. D-Asp, on...
Intersexuality has been reported in pigs and investigations are in progress to identify and physical...
<div><p>Boar taint is an offensive odour and/or taste from a proportion of non-castrated male pigs c...
Despite the fact that pigs are increasingly used in pharmacological and toxicological studies, knowl...
Porcine tissue gene expression is highly similar to the expression of homologous genes in humans. Ba...
Cytochrome P450 (CYP450) is the major family of enzymes involved in the metabolism of several xenobi...