Sixtieth Anniversary of Angiotensin

The journal, very recently, paid tribute to the 100thanniversary of the discovery of renin by Tigerstedtand Bergman.1,2 Forty years later, 2 independent investigative groups in Buenos Aires and Indianapolis, headed by Drs Eduardo Braun-Menèndez and Irvine H. Page, respectively, identified the active polypeptide angiotensin that explained the pressor effect of renal hypertension.3–6 Thus, using relatively unsophisticated methods (in terms of present day technology), the precise peptide that produced experimental renal hypertension was identified. In the accompanying online-only historical commentary, Drs Nidia Basso and Norberto Terragno provide a chrono-logical history of the discovery by the Braun-Menèndez team from the University of Buenos Aires.7 Their account jibes well with an interview of Irvine Page that I taped just prior to his death for the National Library of Medicine under the aegis of a grant-in-aid by the Alpha Omega Alpha medical hono