1W. Marcenes1*, N.J. Kassebaum2,

The Global Burden of Disease (GBD) 2010 Study produced comparable estimates of the burden of 291 diseases and injuries in 1990, 2005, and 2010. This article reports on the global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 and compares those figures with new estimates for 1990. We used disability-adjusted life-years (DALYs) and years lived with disability (YLDs) metrics to quantify burden. Oral conditions affected 3.9 billion people, and untreated caries in permanent teeth was the most prevalent condition evaluated for the entire GBD 2010 Study (global prevalence of 35 % for all ages combined). Oral conditions combined accounted for 15 million DALYs globally (1.9 % of all YLDs; 0.6 % of all DALYs), implying an average health loss of 224 years per 100,000 population. DALYs due to oral conditions increased 20.8 % between 1990 and 2010, mainly due to population growth and aging. While DALYs due to severe periodon-titis and untreated caries increased, those due to severe tooth loss decreased. DALYs differed by age groups and regions, but not by genders. The findings highlight the challenge in responding to the diversity of urgent oral health needs world-wide, particularly in developing communities. KEY WORDS: dental caries, periodontal dis-eases, mouth, edentulous, world health, disabilit