Add to ORKGHepatic microsomal protein. cytochrome P-450. U DP-glucuronyltransferase. ethylmorphine demethylase. aniline hydroxylase. and aryl hydrocarbon hydroxylase levels were measured in the 2-. 4-. 5-. 6-. and 8-month-old Hanford miniature pig. The activities or concentrations of all of the liver parameters measured had apparently reached their adult plateau level by 2 months of age. The use of the miniature pig in toxicology research programs is discussed. The exportation of wild captured Old and New World monkeys is presently being restricted and current evidence indicates that the primate short-age will be more severe in the future. There has been only limited success in domestic primate breeding programs, and the potential for meeting the need...
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Liver microsomes are used extensively in human pharmaceutical development to study the metabolism of...
The pig is not only an economically important livestock animal but is also a valuable model animal f...
Disposition and oral bioavailability studies involving non-rodent animal models traditionally rely u...
We used various substrates and selective inhibitors of human cytochrome P450 (CYP) isozymes as probe...
Since the implementation of several legislations to improve pediatric drug research, more pediatric ...
Since the implementation of several legislations to improve pediatric drug research, more pediatric ...
<p>Since the implementation of several legislations to improve pediatric drug research, more pediatr...
Miniature-pig models for human metabolic disorders such as obesity and metabolic syndrome are gainin...
Introduction: The anatomy and physiology of pigs is closely related to human characteristics. Theref...
Despite the fact that pigs are increasingly used in pharmacological and toxicological studies, knowl...
Pentachloroanisole (PCA), an environmental degradation product of the biocide pentachlorophenol (PCP...
In view of paediatric drug development, regulatory authorities often request safety studies in juven...
The Gottingen Minipig is gaining ground as nonrodent species in safety testing of drugs for pediatri...
1. The aim was to clarify the kinetic and cytochrome P450 (CYP) enzymes involved in l-deprenyl metab...
Abstract: The pig has been used as an important animai model far human studies because of its simila...
Liver microsomes are used extensively in human pharmaceutical development to study the metabolism of...
The pig is not only an economically important livestock animal but is also a valuable model animal f...
Disposition and oral bioavailability studies involving non-rodent animal models traditionally rely u...
We used various substrates and selective inhibitors of human cytochrome P450 (CYP) isozymes as probe...
Since the implementation of several legislations to improve pediatric drug research, more pediatric ...
Since the implementation of several legislations to improve pediatric drug research, more pediatric ...
<p>Since the implementation of several legislations to improve pediatric drug research, more pediatr...
Miniature-pig models for human metabolic disorders such as obesity and metabolic syndrome are gainin...
Introduction: The anatomy and physiology of pigs is closely related to human characteristics. Theref...
Despite the fact that pigs are increasingly used in pharmacological and toxicological studies, knowl...
Pentachloroanisole (PCA), an environmental degradation product of the biocide pentachlorophenol (PCP...
In view of paediatric drug development, regulatory authorities often request safety studies in juven...
The Gottingen Minipig is gaining ground as nonrodent species in safety testing of drugs for pediatri...
1. The aim was to clarify the kinetic and cytochrome P450 (CYP) enzymes involved in l-deprenyl metab...
Abstract: The pig has been used as an important animai model far human studies because of its simila...
Liver microsomes are used extensively in human pharmaceutical development to study the metabolism of...
The pig is not only an economically important livestock animal but is also a valuable model animal f...
Disposition and oral bioavailability studies involving non-rodent animal models traditionally rely u...
