This dissertation describes the research that we have done concerning reversible Markov chains. We first present definitions for what it means for a Markov chain to be reversible. We then give applications of where reversible Markov chains are used and give a brief history of Markov chain inference. Finally, two journal articles are found in the paper, one that is already published and another which is currently being submitted. The first article examines estimation of the one-step-ahead transition probabilities in a re-versible Markov chain on a countable state space. A symmetrized moment estimator is proposed that exploits the reversible structure. Examples are given where the symmetrized estimator has superior asymptotic properties to th...