Understanding the numerous functions that RNAs play in living cells depends critically on knowledge of their three-dimensional structure. Due to the difficulties in experimentally assessing structures of large RNAs, there is currently great demand for new high-resolution structure prediction methods. We present the novel method for the fully automated prediction of RNA 3D structures from a user-defined secondary structure. The concept is founded on the machine translation system. The translation engine operates on the RNA FRABASE database tailored to the dictionary relating the RNA secondary structure and tertiary structure elements. The trans-lation algorithm is very fast. Initial 3D structure is composed in a range of seconds on a single ...
RNA is not regarded anymore as a simple transfer molecule between DNA and proteins. Indeed, over the...
RNA structures are generally organized hierarchically organized. Prediction of RNA structure is a bi...
Abstract: The view of RNA as simple information transfer molecule has been continuously challenged s...
RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes withi...
RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes withi...
With increasing recognition of the roles RNA molecules and RNA/protein complexes play in an unexpect...
Motivation. Over the recent years, the vision that RNA simply serves as information transfer molecul...
The study of RNA structure is fundamental to clarify the RNA molecular functioning. The flexible RNA...
RNA cannot be considered anymore as a simple transfer molecule. On the contrary, a plethora of nonco...
RNA molecules have key functions in cellular processes beyond being carriers of protein-coding infor...
The thesis deals with proposal, implementation and testing of a new algorithm for homologous tertiar...
Here we introduce the Computational Recognition of Secondary Structure (CROSS) method to calculate t...
RNA is a unique biomolecule that is involved in a variety of fundamental biological functions, all o...
Motivation: RNAs fold into complex structures that are integral to the diverse mechanisms under-lyin...
We summarize different levels of RNA structure prediction, from classical 2D structure to extended s...
RNA is not regarded anymore as a simple transfer molecule between DNA and proteins. Indeed, over the...
RNA structures are generally organized hierarchically organized. Prediction of RNA structure is a bi...
Abstract: The view of RNA as simple information transfer molecule has been continuously challenged s...
RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes withi...
RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes withi...
With increasing recognition of the roles RNA molecules and RNA/protein complexes play in an unexpect...
Motivation. Over the recent years, the vision that RNA simply serves as information transfer molecul...
The study of RNA structure is fundamental to clarify the RNA molecular functioning. The flexible RNA...
RNA cannot be considered anymore as a simple transfer molecule. On the contrary, a plethora of nonco...
RNA molecules have key functions in cellular processes beyond being carriers of protein-coding infor...
The thesis deals with proposal, implementation and testing of a new algorithm for homologous tertiar...
Here we introduce the Computational Recognition of Secondary Structure (CROSS) method to calculate t...
RNA is a unique biomolecule that is involved in a variety of fundamental biological functions, all o...
Motivation: RNAs fold into complex structures that are integral to the diverse mechanisms under-lyin...
We summarize different levels of RNA structure prediction, from classical 2D structure to extended s...
RNA is not regarded anymore as a simple transfer molecule between DNA and proteins. Indeed, over the...
RNA structures are generally organized hierarchically organized. Prediction of RNA structure is a bi...
Abstract: The view of RNA as simple information transfer molecule has been continuously challenged s...