Work performed at the Cardiovascular Surgery Discipline of the

Uso tópico de agente antifibrinolítico na redução do sangramento após revascularização cirúrgica do miocárdio Topical use of antifibrinolytic agent to reduce postoperative bleeding after coronary artery bypass surgery Objective: Antifibrinolytic agents reduce bleeding after cardiac surgery, but there are adverse effects after their systemic use. These effects are avoided by topical application of antifibrinolytic agents in pericardial cavity. We compared the effects of topically applied epsilon-aminocaproic acid (EACA) and placebo on postoperative bleeding and transfusion requirements after coronary artery bypass surgery. Methods: In this single center prospective, randomized