ENVIRONMENT AND HEALTH The Effect of Flavophospholipol (Flavomycin) and Salinomycin Sodium (Sacox) on the Excretion of Clostridium perfringens, Salmonella enteritidis, and Campylobacter jejuni in Broilers After Experimental Infection

ABSTRACT Intestinal colonization and shedding of pathogenic bacteria in animal feces is an important factor in both human food safety and animal health. The effect of broiler feed additives flavophospholipol (FPL; Flavo-mycin, bambermycins) and salinomycin sodium (SAL; Sacox) given singly on the excretion of Salmonella enteriti-dis, Campylobacter jejuni, and Clostridium perfringens was studied following controlled infection. The incidence of shedding (number of birds with positive fecal cultures) and the degree of shedding (cfu per gram of feces in positive birds) were measured to determine the influence of these two common feed additive antibiotics on shed-ding rates of potential pathogens. A total of 216 Ross broiler chickens, housed in battery cages, were fed either an unmedicated feed (controls), feed containing FPL, or feed containing SAL. Feed treat