Add to ORKGCombinatorial chemistry (1–7) has drastically modified the drug discovery process by allowing the rapid simultaneous preparation of numerous organic molecules to feed bioassays. Most of the time, syntheses are carried out using solid-phase methodology (8). The target compounds are built on an insolubl
Synthetic peptides have been produced in abundance by resource and research laboratories for both ba...
The advantages and disadvantages of solid-phase chemistry compared to “classical” solution phase che...
Tamoxifen has a backbone structure of triphenylethylene and is a drug that has been used for over 20...
Parallel synthesis on solid-phase is routinely applied in our combinatorial chemistry efforts for le...
A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and techn...
"Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial ...
International audienceMass spectrometry is a powerful analytical tool allowing rapid and sensitive s...
Solid-phase synthesis is a powerful tool for achieving high-throughput chemistry. This review discus...
Lysobactin is an eleven residue cyclic depsi-peptide antibiotic with a two to four fold greater pote...
Both solid- and liquid-phase combinatorial chemistry have emerged as powerful tools for identifying ...
Solid-phase techniques have been introduced in the early sixties by Bruce Merrifield (Nobel Prize in...
Solid-phase peptide synthesis is routinely used in research ranging from the elucidation of chemical...
This chapter focuses on combinatorial chemistry. The synthesis of small peptides, derived from large...
International audienceSupported peptide and drug-like organic molecule libraries were profiled in si...
In the last decade we have seen improved a powerfull tool to medicinal chemistry: the Solid Phase Or...
Synthetic peptides have been produced in abundance by resource and research laboratories for both ba...
The advantages and disadvantages of solid-phase chemistry compared to “classical” solution phase che...
Tamoxifen has a backbone structure of triphenylethylene and is a drug that has been used for over 20...
Parallel synthesis on solid-phase is routinely applied in our combinatorial chemistry efforts for le...
A unique, integrated look at solid-phase synthesis and advances in combinatorial chemistry and techn...
"Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial ...
International audienceMass spectrometry is a powerful analytical tool allowing rapid and sensitive s...
Solid-phase synthesis is a powerful tool for achieving high-throughput chemistry. This review discus...
Lysobactin is an eleven residue cyclic depsi-peptide antibiotic with a two to four fold greater pote...
Both solid- and liquid-phase combinatorial chemistry have emerged as powerful tools for identifying ...
Solid-phase techniques have been introduced in the early sixties by Bruce Merrifield (Nobel Prize in...
Solid-phase peptide synthesis is routinely used in research ranging from the elucidation of chemical...
This chapter focuses on combinatorial chemistry. The synthesis of small peptides, derived from large...
International audienceSupported peptide and drug-like organic molecule libraries were profiled in si...
In the last decade we have seen improved a powerfull tool to medicinal chemistry: the Solid Phase Or...
Synthetic peptides have been produced in abundance by resource and research laboratories for both ba...
The advantages and disadvantages of solid-phase chemistry compared to “classical” solution phase che...
Tamoxifen has a backbone structure of triphenylethylene and is a drug that has been used for over 20...